Digital perioperative rehabilitation for gastric cancer surgery after neoadjuvant therapy
The Effect of Perioperative Rehabilitation Programme Delivered Via a Smart Phone Based Digital Platform in Patients Undergoing Neoadjuvant Therapy for Gastric Cancer Surgery: Study Protocol for a Randomised Controlled Trial
This project tests whether a perioperative multimodal rehabilitation program delivered with a smartphone app or by telephone can reduce postoperative complications and improve recovery for adults with resectable gastric cancer receiving neoadjuvant therapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 186 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Beijing Friendship Hospital Academic / other |
| Locations | 1 site (Beijing) |
| Trial ID | NCT07441850 on ClinicalTrials.gov |
What this trial studies
This randomized interventional trial compares three approaches: multimodal perioperative rehabilitation with digital supervision, the same program with telephone supervision, and usual care for patients undergoing neoadjuvant therapy and surgery for resectable gastric cancer. The rehabilitation program combines exercise, nutritional support, and psychological guidance delivered before and after surgery. Primary endpoints include postoperative complication rates and perioperative clinical indices such as functional capacity (6MWT), nutritional status, and psychological measures, and a key secondary endpoint is patient adherence as tracked by the smartphone platform. Participants are adults aged 18–70 treated at Beijing Friendship Hospital and will attend planned in-person and digital follow-ups.
Who should consider this trial
Good fit: Ideal candidates are adults 18–70 with histologically confirmed resectable gastric or gastroesophageal junction adenocarcinoma referred for neoadjuvant therapy who can use a smartphone and agree to regular follow-up.
Not a fit: Patients with distant metastasis, severe cardiopulmonary disease precluding exercise testing or training, concurrent other malignancies, cognitive or communication barriers, or pregnancy are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, the program could lower postoperative complication rates, speed functional and nutritional recovery, and improve patient adherence to perioperative care.
How similar studies have performed: Prehabilitation approaches have shown benefit in other surgical oncology populations, but smartphone-based digital supervision specifically for gastric cancer perioperative care is less well established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients aged between 18 and 70 years; * patients with histologically confirmed resectable adenocarcinoma of the oesophago gastric junction or stomach; * patients referred by a multidisciplinary team (MDT) for neoadjuvant therapy; * patients able to use a smartphone and the digital follow up platform, and willing to comply with regular follow up assessments; * patients who provide written informed consent. Exclusion Criteria: * presence of distant metastasis; * severe cardiopulmonary disease or other contraindications precluding completion of the 6MWT or participation in exercise training; * concurrent other malignant tumours; * suspected recurrent gastric cancer; * cognitive impairment, communication barriers, or psychiatric conditions that would prevent compliance with the study procedures; * women who are pregnant, lactating, or planning a pregnancy.
Where this trial is running
Beijing
- Beijing Friendship Hospital, Capital Medical University — Beijing, China (Recruiting)
Study contacts
- Study coordinator: Zhi Zheng, Attending surgon
- Email: zhengzhi@ccmu.edu.cn
- Phone: +86-13811132175
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.