Digital intervention to reduce emotional distress in adults with type 2 diabetes

Evaluating a Digital Intervention for Alleviating Diabetes-specific Emotional Distress in Adults Living With Type 2 Diabetes Mellitus: Randomized Controlled Trial

Not applicable Interventional Gaia AG · NCT06529965

This study is testing a new digital program to see if it can help adults with type 2 diabetes feel less emotional distress and better manage their condition.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment250 (estimated)
Ages18 Years and up
SexAll
SponsorGaia AG Industry-sponsored
Locations1 site (Hamburg)
Trial IDNCT06529965 on ClinicalTrials.gov

What this trial studies

This randomized controlled trial involves 250 adults diagnosed with type 2 diabetes mellitus (T2DM) to evaluate the effectiveness of a self-guided digital therapeutic called covivio. Participants will be selected based on their elevated levels of diabetes-specific emotional distress, as measured by the PAID-20 score. The study aims to provide insights into how digital health applications can assist in diabetes self-management and improve emotional well-being. Eligible participants must be at least 18 years old, have sufficient German language skills, and own a CGM-compatible smartphone.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older with a confirmed diagnosis of type 2 diabetes and elevated emotional distress levels.

Not a fit: Patients with type 1 diabetes or those currently using continuous glucose monitoring may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce emotional distress in patients with type 2 diabetes, leading to improved overall health and diabetes management.

How similar studies have performed: Previous studies have shown promise in using digital interventions for diabetes management, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* male, female or non-binary
* age ≥ 18 years
* diagnosis of T2DM secured via submission of a medical certificate attesting to the presence of at least one of the following ICD-10-GM diagnoses of T2DM: E11.20, E11.30, E11.40, E11.50, E11.60, E11.72, E11.74, E11.80, E11.90
* elevated levels of diabetes-specific emotional distress: cut-off ≥ 33 on the PAID-20
* access to CGM-compatible smartphone
* consent to participate
* sufficient knowledge of the German language

Exclusion Criteria:

* diagnosis of type 1 diabetes mellitus (T1DM)
* change in medication (type, frequency of use or dosage) within 4 weeks before the baseline visit or planned within the subsequent 6 months
* recent or planned bariatric operation within 4 weeks before the baseline visit or within the subsequent 6 months
* change in psychotherapeutic treatment within 4 weeks before the baseline visit or planned within the subsequent 6 months
* current use of continuous glucose monitoring (CGM) as part of one's diabetes treatment
* experiencing problems with the CGM sensor or insufficient CGM data quality at baseline (T0) (i.e., wearing the CGM sensor on less than 6 of 7 days, providing less than a minimum of 96 hours of glucose values, providing less than 24 hours overnight CGM data)

Where this trial is running

Hamburg

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Glucose Metabolism DisordersMetabolic DiseaseEndocrine System DiseasesDiabetes Mellitus, Type 2type 2 diabetescoviviodiabetes self-managementdigital health application
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.