Digital cognitive check after a stroke in people with severe disability
Official title: Digital Cognitive Assessment in Stroke Patients for Evaluating Long-Term Cognitive Recovery: The TuCAN App for Patients With Middle Cerebral Artery Ischemia (TuCAN-Media)"
Run by University Hospital Tuebingen · NCT07885189 · Data updated 2026-11-12
This study tests how well a digital cognitive assessment app (TuCAN-App) can track recovery in adults who had a major stroke and were severely disabled.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | University Hospital Tuebingen Academic / other |
| Locations | 1 site (Tübingen) |
| Status | Recruiting |
| Started | July 1, 2025 |
| Main results expected | November 2026 |
| Study ends | February 2027 |
| Registry record updated | October 21, 2026 |
| Trial ID | NCT07885189 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) who had a MCA stroke with severe disability (mRS ≥ 3) and can provide consent or have a representative to consent.
✕Probably not a fit
Patients without a MCA stroke, with lower initial disability, or who are unable to use digital testing may derive little or no direct benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study follows adults with MCA stroke and a modified Rankin Scale score of 3 or higher to monitor cognitive recovery over time. It uses the TuCAN-App to perform multi-domain digital cognitive testing during the acute phase and at 3 and 6 months after the stroke. The aim is to standardize and rapidly assess cognitive function as patients progress, to understand recovery trajectories. Participation involves longitudinal assessments with informed consent provided by patients or their representatives. The study is led by University Hospital Tuebingen, with the Sigrid Oergel Foundation as a collaborator.
Why it matters
Potential benefit: If successful, the digital tool could provide clinicians with timely, standardized insights into cognitive recovery after stroke to guide care and rehabilitation planning.
How similar studies have gone: Previous studies in digital cognitive assessment after stroke have shown feasibility and monitoring value, but this exact approach in MCA-stroke with high disability is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ≥ 18 years of age * Right- or left-hemispheric MCA occlusion (MCA segments M1-M3 or corresponding perfusion deficit) * modified Rankin Scale (mRS) score ≥ 3 at the time of the index event * Informed consent from the patient or their legal representative Exclusion Criteria: * ≤ 18 years of age * Pregnancy * Pre-existing severe dementia
Where it's running
-
Department of Neurology; University Hospital
Tübingen, Germany Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.