Clinical trial Recruiting at 1 site Observational Ages 18 and up

Digital cognitive check after a stroke in people with severe disability

Official title: Digital Cognitive Assessment in Stroke Patients for Evaluating Long-Term Cognitive Recovery: The TuCAN App for Patients With Middle Cerebral Artery Ischemia (TuCAN-Media)"

Run by University Hospital Tuebingen · NCT07885189 · Data updated 2026-11-12

This study tests how well a digital cognitive assessment app (TuCAN-App) can track recovery in adults who had a major stroke and were severely disabled.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment50 (estimated)
SponsorUniversity Hospital Tuebingen
Academic / other
Locations1 site (Tübingen)
StatusRecruiting
StartedJuly 1, 2025
Main results expectedNovember 2026
Study endsFebruary 2027
Registry record updatedOctober 21, 2026
Trial IDNCT07885189 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) who had a MCA stroke with severe disability (mRS ≥ 3) and can provide consent or have a representative to consent.

Probably not a fit

Patients without a MCA stroke, with lower initial disability, or who are unable to use digital testing may derive little or no direct benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study follows adults with MCA stroke and a modified Rankin Scale score of 3 or higher to monitor cognitive recovery over time. It uses the TuCAN-App to perform multi-domain digital cognitive testing during the acute phase and at 3 and 6 months after the stroke. The aim is to standardize and rapidly assess cognitive function as patients progress, to understand recovery trajectories. Participation involves longitudinal assessments with informed consent provided by patients or their representatives. The study is led by University Hospital Tuebingen, with the Sigrid Oergel Foundation as a collaborator.

Why it matters

Potential benefit: If successful, the digital tool could provide clinicians with timely, standardized insights into cognitive recovery after stroke to guide care and rehabilitation planning.

How similar studies have gone: Previous studies in digital cognitive assessment after stroke have shown feasibility and monitoring value, but this exact approach in MCA-stroke with high disability is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥ 18 years of age
* Right- or left-hemispheric MCA occlusion (MCA segments M1-M3 or corresponding perfusion deficit)
* modified Rankin Scale (mRS) score ≥ 3 at the time of the index event
* Informed consent from the patient or their legal representative

Exclusion Criteria:

* ≤ 18 years of age
* Pregnancy
* Pre-existing severe dementia

Where it's running

  • Department of Neurology; University Hospital
    Tübingen, Germany
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.