Different IV Fluids After Surgery for Chronic Subdural Hematoma

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study explores whether postoperative intravenous fluids influence the recurrence of chronic subdural hematoma (CSDH) after burr hole drainage. By administering dextrose 5% in 1/4 normal saline, the study aims to expand brain tissue and reduce the residual cavity, potentially lowering recurrence rates. The trial will compare recurrence risk and remaining hematoma cavity in relation to the fluid strategy and other known risk factors. Outcomes include volume changes on imaging and the need for additional surgery within 3 months or after. The study is conducted at a single center and has no designated control group described.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of chronic subdural hematoma (based on imaging)
* Need for surgical intervention (assessed by attending neurosurgeon based on full neurological assessment)
* The procedure of choice is burr hole drainage
* Cessation of anti-coagulant therapy with accompanying normal lab values in appropriate time frames respective to the drug
* Tolerance of supine position

Exclusion Criteria:

* \<60 years old
* Presence of acute hemorrhage, stroke, or parenchymal damage
* Neurological deficits not accountable to mass effect
* Hyponatremia or inherent electrolyte imbalances
* Pregnancy or non-consentable patients
* Previous neurological surgery up to 1 year before being considered for the study
* Rapid re-expansion of brain observed intraoperatively by attending neurosurgeon
* Congestive heart failure or other medical conditions precluding normal postoperative administration of IV fluids
* Blood glucose levels \> 135 mg/dL

Where it's running

• Carilion Roanoke Memorial Hospital
  Roanoke, Virginia, United States Recruiting

Study contacts

• Principal investigator: Eric Marvin, DO — Carilion Clinic
• Study coordinator: Eric A Marvin, DO
• Email: eamarvin@carilionclinic.org
• Phone: 5405889711

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.