Diet's impact on sperm quality and fertility
Official title: Molecular Mechanisms for Male Fertility: Can Diet Change Sperm sncRNA and the Reproductive Potential?
Run by Ostergotland County Council, Sweden · NCT06831292 · Data updated 2026-11-12
This study is testing if following a Nordic diet can improve sperm quality in men who are part of infertile couples undergoing IVF treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 23 Years to 56 Years |
| Sex | Men only |
| Enrollment | 100 (estimated) |
| Sponsor | Ostergotland County Council, Sweden Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Linköping, Östergötland County) |
| Status | Recruiting |
| Started | December 26, 2024 |
| Main results expected | December 2026 |
| Study ends | December 2027 |
| Registry record updated | May 5, 2026 |
| Trial ID | NCT06831292 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are male partners in infertile couples scheduled for their first IVF treatment who can adhere to dietary guidelines.
✕Probably not a fit
Patients with a history of malignant disease, genetic disorders, or those who cannot comply with dietary restrictions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of a diet intervention based on Nordic dietary guidelines on sperm quality and small non-coding RNA profiles in men undergoing IVF treatment. Males in infertile couples will be randomized into either a control group or a diet intervention group, where they will receive groceries and meal plans tailored to their energy needs during the hormonal treatment period of their female partners. Sperm samples will be collected before and after the intervention to assess changes in quality and RNA profiles. The goal is to determine if dietary changes can enhance reproductive success.
Why it matters
Potential benefit: If successful, this intervention could improve sperm quality and increase the chances of successful IVF outcomes for couples facing infertility.
How similar studies have gone: Previous studies have shown that dietary changes can rapidly affect sperm quality, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male (biological) partner in infertile couple, scheduled for first IVF treatment * Mature sperm cells in semen * Able to speak and read Swedish * Omnivore * Will refrain from nicotine and alcohol during intervention * Sperm sampled provided no more than 3 weeks before intervention start Exclusion Criteria: * Former or present malignant disease * Former radiotherapy in pelvic area * Former chemotherapy * Known genetic/chromosomal disorder * Food allergy
Where it's running
-
University Hospital
Linköping, Östergötland County, Sweden Recruiting
Study contacts
- Study coordinator: Susanne Liffner, M.D, Ph.D.
- Email: susanne.liffner@liu.se
- Phone: +46 (0)101030000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.