Dietary composition effects on appetite and energy regulation
Do Dietary Patterns Influence Your Weight Management and Circadian Rhythms?
NA · Brigham and Women's Hospital · NCT05800990
This study is testing how different types of diets affect hunger and energy use to help people manage obesity better.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 24 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | Brigham and Women's Hospital (other) |
| Locations | 1 site (Boston, Massachusetts) |
| Trial ID | NCT05800990 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to investigate how different dietary compositions influence food intake rhythms, appetite regulation, and energy expenditure. Participants will undergo two field-based dietary interventions and two inpatient stays, during which they will consume standard meals and provide various biological samples. The study seeks to understand the connection between diet and the circadian system to develop evidence-based dietary interventions for obesity management.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-45 with a BMI between 18.5 and 29.9 who do not have any acute or chronic medical conditions.
Not a fit: Patients with significant medical conditions, food allergies, or those on specific diets may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to effective dietary strategies for weight management and obesity prevention.
How similar studies have performed: Previous studies have shown promising results in understanding the relationship between diet and circadian rhythms, but this specific approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-45 yr old * BMI 18.5-29.9 * No acute, chronic or debilitating medical conditions (e.g. metabolic, cardiovascular, respiratory, neurological, cancers, etc.) * Without medication use (except oral contraceptives) Exclusion Criteria: * Currently smoking/vaping or 5 or more years of smoking/vaping * History of drug or alcohol dependency * History of psychiatric illness or disorder * People with food allergies/intolerances or following specific diets
Where this trial is running
Boston, Massachusetts
- Brigham and Women's Hospital — Boston, Massachusetts, United States (RECRUITING)
Study contacts
- Principal investigator: Frank AJL Scheer, PhD — Brigham and Women's Hospital
- Study coordinator: Frank A.J.L. Scheer, PhD
- Email: FSCHEER@BWH.HARVARD.EDU
- Phone: 617-732-7014
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Dietary Intervention, circadian rhythm, energy expenditure, appetite regulation