Dexmedetomidine vs remifentanil as anesthesia aids for ECT

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional phase 4 trial compares two anesthetic adjuncts, dexmedetomidine and remifentanil, with saline as a control, in patients undergoing six ECT sessions. The goal is to see which option most effectively moderates acute hemodynamic responses while preserving seizure quality and enabling rapid recovery. Participants are adults aged 18–60 with ASA I–II undergoing ECT for various psychiatric conditions. Outcomes focus on hemodynamic stability, seizure duration/quality, and recovery profile, with safety monitoring for drug-related adverse events. The study builds on prior use of these agents to improve intraoperative stability and minimize sympathetic activation during ECT.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Upremedicated ASA I-II (American Society of Anesthesiologists's physical status) patients,
* Patients scheduled for six ECT sessions for a variety of psychiatric conditions

Exclusion Criteria:

* refusal to participate,
* age below 18 or above 60 years
* pregnancy
* asthma
* current use of β-adrenergic blockers
* myocardial infarction within the previous six months
* atrial fibrillation or atrial flutter,
* heart block
* a known personal or family history of hypersensitivity to any of the study drugs

Where it's running

• Inonu Universitesi Turgut Ozal Tıp Merkezi
  Malatya, Battalgazi, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Zekine Begeç, Prof.Dr
• Email: zekine.begec@inonu.edu.tr
• Phone: 904223410660

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.