Dexmedetomidine-augmented nerve block to help kids after posterior fossa tumor surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares four approaches to a greater occipital nerve block in children undergoing posterior fossa tumor excision: blind versus ultrasound-guided technique and with or without Dexmedetomidine as an adjuvant. It is designed to see if ultrasound guidance improves hemodynamic stability and whether adding Dexmedetomidine lowers intraoperative and postoperative opioid use and shortens time to first rescue analgesia. Participants are pediatric patients with ASA II-III status, undergoing elective surgery, randomized into four groups. Outcomes include pain control, analgesic consumption, and time to first analgesic request. The study is conducted at a single center, Children's Cancer Hospital Egypt 57357.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pediatric patient undergoing elective posterior fossa tumor excision.
* ASA physical status II-III.
* Informed consent obtained from parents or legal guardians.

Exclusion Criteria:

* Allergy to study drugs (Bupivacaine - Dexmedetomidine)
* Local infection at the site of injection.
* Coagulopathy or use of anticoagulants.
* Pre-existing neurologic deficits that interfere with postoperative pain assessment.
* Developmental delay preventing appropriate pain evaluation.
* Hemodynamic instability prior induction.

Where it's running

• Children's Cancer Hospital 57357
  Cairo, Egypt Recruiting

Study contacts

• Principal investigator: Reham Gamal — Children's cancer hospital 57357
• Study coordinator: Nancy Ashraf Abdellatif
• Email: nancy.ashraf@57357.com
• Phone: +201141083507

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.