Development of MRI protocols for radiotherapy planning
MRI Development for Radiotherapy Planning and Delivery in Non-Patient Volunteers
This study is testing new MRI scanning methods to improve how doctors plan and deliver radiotherapy for cancer patients, using non-patient volunteers.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 16 Years and up |
| Sex | All |
| Sponsor | The Christie NHS Foundation Trust Academic / other |
| Locations | 1 site (Manchester) |
| Trial ID | NCT04749134 on ClinicalTrials.gov |
What this trial studies
This study involves non-patient volunteers who will undergo MRI scans using advanced MR-Linac and MRSIM technologies. The primary aim is to develop, optimize, and validate MRI protocols that can enhance radiotherapy planning and delivery. Participants will be required to provide written consent and undergo MRI safety screening, with their scans being read by a clinical radiologist for any incidental findings. The study is observational and does not involve any treatment interventions.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 16 and older who are willing to participate as non-patient volunteers and can safely undergo MRI scans.
Not a fit: Patients with contraindications to MRI or those who are unable to tolerate an MRI scan will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved MRI protocols that enhance the accuracy and effectiveness of radiotherapy for cancer patients.
How similar studies have performed: While this study focuses on MRI protocol development, similar studies have shown promise in enhancing imaging techniques for radiotherapy, indicating a potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Willing and able to provide written consent * Volunteers must undergo and satisfy MRI safety screening * Volunteers must be ≥ 16 years of age * Participants must agree to registration as a non-patient in CWP (the Trust's Electronic Health Record - EHR- system) and have their MRIs read and reported for incidental findings by a clinical radiologist Exclusion Criteria: * Any contraindications to MRI identified after MRI safety screening including completion of an MRI Safety Screening Form * Unable to tolerate MRI scan * Known Pregnancy * Known or suspected pathology in body region to be scanned * Member of study team
Where this trial is running
Manchester
- The Christie NHS FT — Manchester, United Kingdom (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.