Clinical trial Recruiting at 1 site Observational Ages 16 and up

Development of MRI protocols for radiotherapy planning

Official title: MRI Development for Radiotherapy Planning and Delivery in Non-Patient Volunteers

Run by The Christie NHS Foundation Trust · NCT04749134 · Data updated 2026-11-12

This study is testing new MRI scanning methods to improve how doctors plan and deliver radiotherapy for cancer patients, using non-patient volunteers.

Quick facts

Study typeObservational
Ages16 Years and up
SexAll
Enrollment500 (estimated)
SponsorThe Christie NHS Foundation Trust
Academic / other
Locations1 site (Manchester)
StatusRecruiting
StartedAugust 1, 2021
Main results expectedAugust 31, 2028
Study endsAugust 31, 2028
Registry record updatedAugust 24, 2025
Trial IDNCT04749134 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 16 and older who are willing to participate as non-patient volunteers and can safely undergo MRI scans.

Probably not a fit

Patients with contraindications to MRI or those who are unable to tolerate an MRI scan will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study involves non-patient volunteers who will undergo MRI scans using advanced MR-Linac and MRSIM technologies. The primary aim is to develop, optimize, and validate MRI protocols that can enhance radiotherapy planning and delivery. Participants will be required to provide written consent and undergo MRI safety screening, with their scans being read by a clinical radiologist for any incidental findings. The study is observational and does not involve any treatment interventions.

Why it matters

Potential benefit: If successful, this study could lead to improved MRI protocols that enhance the accuracy and effectiveness of radiotherapy for cancer patients.

How similar studies have gone: While this study focuses on MRI protocol development, similar studies have shown promise in enhancing imaging techniques for radiotherapy, indicating a potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Willing and able to provide written consent
* Volunteers must undergo and satisfy MRI safety screening
* Volunteers must be ≥ 16 years of age
* Participants must agree to registration as a non-patient in CWP (the Trust's Electronic Health Record - EHR- system) and have their MRIs read and reported for incidental findings by a clinical radiologist

Exclusion Criteria:

* Any contraindications to MRI identified after MRI safety screening including completion of an MRI Safety Screening Form
* Unable to tolerate MRI scan
* Known Pregnancy
* Known or suspected pathology in body region to be scanned
* Member of study team

Where it's running

  • The Christie NHS FT
    Manchester, United Kingdom
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.