Developing a prediction model for selecting patients with sarcoma
Official title: Swiss Sarcoma Network: Prediction Model for Patient Selection in Sarcoma Care
Run by Kantonsspital Winterthur KSW · NCT04300257 · Data updated 2026-11-12
This study is trying to create a model that helps doctors choose the best treatment options for people with sarcoma based on their individual characteristics and tumor types.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Kantonsspital Winterthur KSW Academic / other |
| Locations | 8 sites (Winterthur, Canton of Zurich and 7 other locations) |
| Status | Recruiting |
| Started | October 19, 2019 |
| Main results expected | December 31, 2029 |
| Study ends | December 31, 2029 |
| Registry record updated | March 20, 2024 |
| Trial ID | NCT04300257 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals of all ages with malignant, intermediate, or selected benign bone or soft tissue tumors.
✕Probably not a fit
Patients who have documented objections to the use of their personal health data may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project aims to analyze various aspects of sarcoma care, including diagnostics, treatment, and follow-up. Through interdisciplinary collaboration, the study will develop predictive and prognostic criteria to enhance treatment outcomes for patients with sarcoma. The analysis will focus on patient characteristics, tumor types, histology, management strategies, recurrence rates, and overall survival. The goal is to create a model that can guide future patient selection for different diagnostic and treatment procedures.
Why it matters
Potential benefit: If successful, this study could lead to more personalized and effective treatment strategies for patients with sarcoma.
How similar studies have gone: Other studies have shown success in developing predictive models for cancer treatment, indicating potential for this approach in sarcoma care.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Malignant and intermediate and selected benign bone or soft tissue tumors, acc. to the WHO coding list of the SSN * Female and male subjects of all ages Exclusion Criteria: * Documented objection of subsequent use of personal health data
Where it's running
-
Kantonsspital Winterthur
Winterthur, Canton of Zurich, Switzerland Recruiting -
SwissSarcomaNetwork
Winterthur, Canton of Zurich, Switzerland Recruiting -
Ente Ospedaliero Cantonale
Bellinzona, Canton Ticino, Switzerland Recruiting -
Kantonsspital Graubünden
Chur, Kanton Graubünden, Switzerland Recruiting -
Luzerner Kantonsspital
Lucerne, Switzerland Recruiting -
Pathologie Institut Enge
Zurich, Switzerland Recruiting
Show 2 more locations
-
Klinik Hirslanden
Zurich, Switzerland Recruiting -
Stadtspital Zürich Triemli
Zurich, Switzerland Recruiting
Study contacts
- Principal investigator: Bruno Fuchs, Prof — SwissSarcomaNetwork
- Study coordinator: Bruno Fuchs, Prof.
- Email: bruno.fuchs@ksw.ch
- Phone: +41 52 266 25 33
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
MIGHTY: CAR T cells targeting B7-H3 for pediatric, teen, and young adult sarcoma
This Phase 1 trial tests autologous hBRCA84D CAR T cells in kids, teens, and young adults (1–24) with relapsed or refractory RMS, ES, or DSRCT to see if the therapy is feasible and safe.
-
Lifileucel (Tumor-infiltrating lymphocytes) for advanced soft tissue sarcoma
This study tests lifileucel, a cell therapy made from a patient’s own tumor cells, in adults with unresectable or metastatic soft tissue sarcoma who have had prior treatments to see if it helps shrink tumors and improve outcomes.
-
Domatinostat with Sirolimus for relapsed or refractory sarcoma and osteosarcoma
This study tests whether the cancer drugs domatinostat and sirolimus together can help adolescents and adults whose sarcoma or osteosarcoma has come back or stopped responding to standard therapy.
-
Clonal Hematopoiesis Effects with Chemo and Radiation in Solid Cancers
This study tests whether clonal hematopoiesis affects outcomes for adults with solid cancers who are receiving chemotherapy or radiation.
-
AYA Sarcoma Survivors: Personalized Exercise Program Pilot
This pilot tests a personalized 12-week exercise program for adolescents and young adults with sarcoma to see if a triage tool can connect them with the right rehabilitation and exercise services.
-
Fluorescence-guided surgery to reduce unexpected positive margins in high-grade sarcoma
This phase II trial tests whether adding fluorescence-guided surgery with indocyanine green can lower unexpected positive margins in patients with high-grade sarcoma compared to standard surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.