Determining the best waiting time for esophagogastroduodenoscopy after lidocaine spray

The Optimal Timing of the Initiation of Esophagogastroduodenoscopy After Oral Lidocaine Spray

Not applicable Interventional National Cheng-Kung University Hospital · NCT06497296

This study is testing whether waiting 1 minute or 3 minutes after using lidocaine spray makes patients more comfortable during an esophagogastroduodenoscopy (EGD).

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment160 (estimated)
Ages20 Years to 90 Years
SexAll
SponsorNational Cheng-Kung University Hospital Academic / other
Locations1 site (Tainan, Other (Non U.s.))
Trial IDNCT06497296 on ClinicalTrials.gov

What this trial studies

This study investigates the optimal waiting time between the application of lidocaine spray and the initiation of esophagogastroduodenoscopy (EGD) to enhance patient comfort and compliance. Participants will be divided into two groups, receiving either a 1-minute or a 3-minute waiting period after the lidocaine application before the EGD procedure begins. The study will monitor vital signs such as heart rate and blood pressure during the procedure and assess the quality of the EGD through patient questionnaires. The goal is to standardize the waiting time to improve the overall quality and safety of the EGD examination.

Who should consider this trial

Good fit: Ideal candidates are patients aged 20 years and older scheduled for EGD due to conditions like dyspepsia, peptic ulcer disease, GERD, or diarrhea.

Not a fit: Patients with gastrointestinal bleeding or those requiring emergency procedures will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved patient comfort and reduced complications during EGD procedures.

How similar studies have performed: While there may be studies on sedation and anesthesia in EGD, this specific investigation into the timing of lidocaine application is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Eligible participants included patients aged ≥ 20 years who scheduled EGD from OPD for dyspepsia, peptic ulcer disease, GERD, subepithelial lesion evaluation, and diarrhea

Exclusion Criteria:

* GI bleeding
* endoscopic submucosal dissection due to prolonged scheduled procedure time
* patients from emergency department or ward

Where this trial is running

Tainan, Other (Non U.s.)

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Blood PressureTachycardia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.