Detecting sepsis using blood fluorescence technology

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore a novel blood fluorescence metabolite analyzer designed to detect early signs of sepsis by identifying inflammatory free radicals in the blood. By employing a case-control methodology, the study will compare blood samples from healthy individuals, septic patients, and non-septic severe patients to assess the analyzer's sensitivity and accuracy. The goal is to enable rapid diagnosis of sepsis before organ damage occurs, potentially reducing mortality rates associated with this condition. The study will involve frequent screenings of blood samples to validate the effectiveness of this reagent-free technology.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Healthy control group: Individuals who are physically healthy with no underlying diseases and have not been hospitalized within the past two years. Recruitment for healthy volunteers will be conducted through notices and online media.
2. Sepsis Experimental Group: Patients with confirmed infections, having qSOFA ≥ 2 and SOFA ≥ 2, will be screened and confirmed by a physician to meet the inclusion criteria.
3. Non-septic Severe Control Group: Patients with suspected or confirmed infections, having a SOFA score of 1, will be screened and confirmed by a physician to meet the inclusion criteria.

Exclusion Criteria: minors, pregnant, individuals with mental illnesses, and other vulnerable groups.

Where it's running

• zhujiang Hospital
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Ning Zeng, Doctor
• Email: chen_ning16@foxmail.com
• Phone: 13760694012

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.