Detecting high blood pressure in hospitalized patients
In-Hospital Detection of Elevated Blood Pressure (INDEBP): Prevalence of New or Uncontrolled Hypertension and Safety of Postponement of Antihypertensive Treatment Adaption in Medical In-patients
NA · University Hospital, Basel, Switzerland · NCT06132451
This study is testing if delaying changes to high blood pressure treatment for hospitalized patients until after they leave the hospital is safe and if their in-hospital blood pressure readings predict their blood pressure after discharge.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 800 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Basel, Switzerland (other) |
| Locations | 1 site (Basel) |
| Trial ID | NCT06132451 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to analyze the prevalence of new or uncontrolled arterial hypertension in patients who had elevated blood pressure during their hospital stay. It investigates whether these elevated blood pressure values correlate with hypertension after discharge and assesses the safety of delaying changes to antihypertensive treatment until after proper evaluation post-discharge. Participants will either receive treatment based on their physician's decision or have their treatment postponed until after they leave the hospital.
Who should consider this trial
Good fit: Ideal candidates are hospitalized patients with asymptomatic elevated blood pressure values who are not admitted for cardiovascular issues.
Not a fit: Patients hospitalized for conditions that could be worsened by uncontrolled hypertension, such as acute coronary syndrome or heart failure, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management of hypertension in patients after hospital discharge.
How similar studies have performed: While there is ongoing research in hypertension management, this specific approach of postponing treatment adaptations post-discharge is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient hospitalized on the internal medicine ward for non-cardiovascular causes, i.e. patients hospitalized for conditions, which are not acutely worsened by uncontrolled AHT * Asymptomatic elevated BP values (defined as 140-180 mmHg systolic and/or 90-110 mmHg diastolic) on at least 2 occasions * Ability to understand study procedures and to provide written informed consent Exclusion Criteria: * Hospitalization for any conditions which can be worsened by uncontrolled AHT: * Cerebrovascular events * Acute coronary syndrome * Acute or decompensated heart failure * Any condition preventing ABPM * Pregnant or lactating women * Failure to provide informed consent
Where this trial is running
Basel
- University Hospital Basel — Basel, Switzerland (RECRUITING)
Study contacts
- Study coordinator: Annina Vischer, M.D.
- Email: annina.vischer@usb.ch
- Phone: +41612652525
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Hypertension, Blood Pressure, High, arterial hypertension, elevated blood pressure, ambulatory blood pressure measurement, antihypertensive medication