Detecting hidden small airway issues in cystic fibrosis patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify unsuspected small airways obstruction in children and adults with cystic fibrosis who have normal routine spirometry results. It utilizes retrospective analysis based on previous research that demonstrated the ability to detect airflow limitations at low lung volumes, despite normal FEV1 and FVC values. The study focuses on the correlation between abnormal expiratory airflow and the presence of bronchiectasis as shown in lung CT scans. By analyzing these factors, the researchers hope to improve the understanding of lung function in cystic fibrosis patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Heterozygote or homozygote patients with cystic fibrosis with normal routine pre bronchodilator spirometry including normal FEV1(L), FVC(L) and FEV1/FVC%.

Exclusion Criteria:Heterozygote or homozygote patients with cystic fibrosis with ABNORMAL routine pre bronchodilator spirometry

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Where it's running

• Arthur F Gelb MD
  Lakewood, California, United States Recruiting
• Miller Children's Hospital and Long Beach Medical Center
  Long Beach, California, United States Recruiting

Study contacts

• Principal investigator: Arthur Gelb, MD — University of California, Los Angeles
• Study coordinator: Arthur F Gelb, MD
• Email: afgelb@msn.com
• Phone: 562-565-5333

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  This study is testing a new MRI method to see how well children with mild cystic fibrosis breathe compared to healthy kids their age.

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• Inhaled CFTR mRNA for cystic fibrosis in Chinese patients aged 12 and older

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  Recruiting Early Phase 1 Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT07485543

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.