Detailed health profiling for people with PCOS
Official title: Phenotyping of Patients With Polycystic Ovary Syndrome (PCOS) in Alsace, France
Run by University Hospital, Strasbourg, France · NCT07339930 · Data updated 2026-11-12
This effort will collect clinical, hormonal (including AMH), and imaging information from adult women seen at Strasbourg University Hospital with suspected or confirmed PCOS to try to better define PCOS types.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 49 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | University Hospital, Strasbourg, France Academic / other |
| Locations | 1 site (Strasbourg) |
| Status | Recruiting |
| Started | September 17, 2025 |
| Main results expected | September 2026 |
| Study ends | September 17, 2026 |
| Registry record updated | January 14, 2026 |
| Trial ID | NCT07339930 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adult women aged 18 to under 50 who consult the Endocrinology department at Strasbourg University Hospital with suspected PCOS or who are found to have PCOS during evaluation.
✕Probably not a fit
People whose final diagnosis excludes PCOS, those younger than 18 or 50 and older, and those unable to attend CHU de Strasbourg appointments will not directly benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational project will enroll adult women (18–49 years) who consult the Endocrinology department at CHU de Strasbourg for suspected PCOS or are found to have PCOS during endocrine care. Participants will have standardized collection of medical history, menstrual and reproductive data, hormone measurements including anti-Müllerian hormone (AMH), pelvic ultrasound morphology, and screening for metabolic risk and mood symptoms. No treatments are given as part of the protocol; data will be analyzed to identify clinical and biochemical phenotypes and how they relate to current diagnostic criteria. The aim is to reduce diagnostic delay and clarify feature clusters that could guide more personalized management in the future.
Why it matters
Potential benefit: If successful, this could help clinicians diagnose PCOS earlier and tailor care to specific PCOS subtypes, potentially improving fertility and metabolic management.
How similar studies have gone: Numerous prior observational cohorts have characterized PCOS phenotypes and supported AMH and ultrasound as useful markers, so this study builds on established but still-evolving evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult woman (≥18 years and \<50 years) * Subject who consulted at the Strasbourg University Hospitals for suspected PCOS or for any other endocrinological condition that led to the discovery of PCOS. Exclusion Criteria: * Final diagnosis excluding PCOS.
Where it's running
-
ervice d'Endocrinologie, Diabétologie et Nutrition - CHU de Strasbourg - France
Strasbourg, France Recruiting
Study contacts
- Study coordinator: Thibault BAHOUGNE, MD
- Email: thibault.bahougne@chru-strasbourg.fr
- Phone: 33 3.88.12.78.99
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Using LC-MS/MS to profile androgens for PCOS diagnosis
This study tests whether LC-MS/MS measurement of androgen profiles can help diagnose PCOS in women compared with healthy controls.
-
Brown adipose tissue responses in PCOS with infrared thermography and inositol
This study tests whether brown fat activity, measured by infrared skin temperature and UCP-1 levels, differs among women with PCOS (normal weight or overweight/obese) and healthy controls, and whether 12 weeks of inositol changes those responses in overweight/obese PCOS participants.
-
Risk tool for blood-clotting problems in adolescents and women with PCOS
This project will try to build a risk model to spot decreased protein C or S and other clotting abnormalities in females aged 14–45 who have PCOS.
-
Polycystic Ovary Syndrome in Type 1 Diabetes
This study tests whether women with type 1 diabetes and PCOS differ from other groups in factors that drive androgen excess and what that means for health.
-
PPOS versus GnRH antagonist IVF protocols for women with PCOS
This trial will test whether a progestin-primed ovarian stimulation (PPOS) protocol or a GnRH antagonist protocol gives better IVF outcomes for women aged 18–40 with PCOS.
-
Tirzepatide for improving reproductive function and metabolic health in overweight women with PCOS
We will test whether tirzepatide can improve menstrual regularity and metabolic health in premenopausal women with PCOS who are overweight or have obesity.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.