Deriving human embryonic stem cell lines from embryos tested for genetic abnormalities

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on isolating human embryonic stem cells (hESCs) from embryos that have been diagnosed as abnormal through preimplantation genetic diagnosis (PGD). The approach involves using embryos that would typically be discarded after IVF procedures, thereby providing an ethically viable source of hESCs for research. These stem cells have the potential to proliferate indefinitely and differentiate into various cell types, making them valuable for studying developmental biology and potential therapies for degenerative diseases. The research aims to create new hESC lines that can be shared with scientists globally for further investigation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Couple has derived embryos by IVF.
* Couple has tested these embryos by PGD and does not want to utilize the embryos to build their families.
* Couple signs informed consent.

Exclusion Criteria:

* Couple does not sign informed consent.

Where it's running

• Hadassah Medical Organization
  Jerusalem, Israel Recruiting

Study contacts

• Principal investigator: Benjamin E. Reubinoff, M.D. PhD. — Hadassah Medical Organization
• Study coordinator: Benjamin E. Reubinoff, M.D. PhD.
• Email: reubinof@md.huji.ac.il
• Phone: 011-972-2-677-7111

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.