Delivery time and umbilical cord blood gases in C-sections with general versus spinal anesthesia
Effect of Neonatal Delivery Time on Umbilical Cord pH and Base Excess in Patients Undergoing Cesarean Section Under General and Spinal Anesthesia
This study will see if the time from uterine incision to delivery affects umbilical artery pH and base excess in adults aged 18–40 having elective C-sections under general or spinal anesthesia.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | Female |
| Sponsor | Sisli Hamidiye Etfal Training and Research Hospital Academic / other |
| Locations | 1 site (Muş) |
| Trial ID | NCT07321041 on ClinicalTrials.gov |
What this trial studies
This is a prospective, observational study at a single tertiary center enrolling adult pregnant women with singleton term pregnancies scheduled for elective cesarean delivery. The choice of general or spinal anesthesia is made by routine clinical care and not altered for the study. The interval from uterine incision to complete delivery will be recorded, and umbilical artery blood gas samples will be obtained immediately after birth to measure pH and base excess. Researchers will compare the relationship between delivery time and cord blood gas values between cases done under general anesthesia and those done under spinal anesthesia, with all data anonymized for analysis.
Who should consider this trial
Good fit: Adults aged 18–40 with a singleton term pregnancy (≥36+6 weeks) scheduled for an elective cesarean section under planned general or spinal anesthesia who can give written informed consent.
Not a fit: Patients undergoing emergency cesarean delivery, multiple pregnancies, known fetal anomalies, significant maternal comorbidities (e.g., diabetes, hypertension, preeclampsia), or those who require conversion from spinal to general anesthesia are unlikely to benefit from this observational comparison.
Why it matters
Potential benefit: If successful, the findings could help clinicians understand whether delivery speed or anesthesia type influences newborn acid-base status and inform practices to reduce fetal acid-base disturbances during elective C-sections.
How similar studies have performed: Previous observational studies have examined delivery intervals and cord blood gases with mixed results, so this approach is not entirely novel but adds comparative data on general versus spinal anesthesia.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Pregnant women aged 18-40 years Singleton pregnancy at ≥36+6 weeks of gestation Scheduled for elective cesarean section Planned delivery under general or spinal anesthesia Ability to provide written informed consent \- Exclusion Criteria: Emergency cesarean section Known fetal anomalies Multiple pregnancy Maternal comorbidities that may affect neonatal outcomes (e.g., diabetes mellitus, hypertension, preeclampsia) Conversion from spinal anesthesia to general anesthesia Failure to obtain umbilical artery blood gas sample or incomplete clinical data
Where this trial is running
Muş
- Mus State Hospital — Muş, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Murat Sahin, Medical Doctor
- Email: mrtshn52@gmail.com
- Phone: +905070666680
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.