DeepComp: AI prediction of complications after stomach cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, multicenter observational study will enroll adults with histologically confirmed gastric adenocarcinoma who are scheduled for elective radical gastrectomy. Researchers will collect routine preoperative contrast-enhanced abdominal CT scans (venous phase) performed within 14 days before surgery plus standard clinical data, then extract radiomic features and body-composition measures (muscle and fat distribution). The DeepComp AI model will integrate these imaging-derived features with clinical variables to generate preoperative risk predictions for moderate-to-severe postoperative complications. Predicted risks will be compared with actual postoperative outcomes to validate the model's performance across participating centers.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Age ≥ 18 years.

Histologically confirmed gastric adenocarcinoma.

Scheduled for elective radical gastrectomy (open, laparoscopic, or robotic) with curative intent.

Standard preoperative contrast-enhanced abdominal CT scans (venous phase) performed within 14 days prior to surgery.

Willingness to sign informed consent.

Exclusion Criteria:

Emergency surgery due to perforation, obstruction, or massive bleeding.

Intraoperative findings of distant metastasis (Stage IV) or unresectable disease preventing R0 resection.

Concurrent or previous malignant tumors within the last 5 years (except gastric cancer).

Pregnancy or lactation.

Severe metallic artifacts on CT images preventing radiomic analysis.

Where it's running

• the Fourth Hospital of Hebei Medical University
  Shijiazhuang, None Selected, China Recruiting

Study contacts

• Principal investigator: Qun Zhao — th
• Study coordinator: Ping'an Ding, PhD
• Email: ding_ping_an@hebmu.edu.cn
• Phone: +8631186095363

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.