Database for understanding cachexia in colon cancer patients
Development of a Prospective Clinico-biological Database in Cachexia in Patients With Colon Cancer
NA · Institut du Cancer de Montpellier - Val d'Aurelle · NCT05257135
This study is trying to gather information about weight loss and nutrition in colon cancer patients to see how it affects their treatment and overall health.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Institut du Cancer de Montpellier - Val d'Aurelle (other) |
| Drugs / interventions | chemotherapy, sunitinib |
| Locations | 1 site (Montpellier) |
| Trial ID | NCT05257135 on ClinicalTrials.gov |
What this trial studies
This study aims to create a prospective clinico-biological database focused on cachexia and undernutrition in patients with colon cancer. It seeks to enhance knowledge about the relationship between colon cancer and cachexia, which is a severe syndrome characterized by significant weight loss and metabolic changes. By collecting biological samples and clinical data, the study intends to optimize therapeutic management and improve patient outcomes. The research will also explore the impact of nutritional approaches on the well-being and survival of these patients.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with colon cancer who are not eligible for surgery and are receiving treatment.
Not a fit: Patients requiring surgery for colon cancer or those with exclusive peritoneal carcinomatosis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies and better management of cachexia in colon cancer patients.
How similar studies have performed: While cachexia in cancer patients is a recognized issue, this specific approach to creating a clinico-biological database is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age ≥ 18 years old, 2. Patient treated at the Montpellier Regional Cancer Institute for colon cancer not eligible for surgery (of the primary tumor or associated metastases), whether undergoing treatment or not, 3. Patient requiring treatment for colon cancer (chemotherapy, targeted therapy, etc.), 4. Patient having accepted the constraints of the research and the blood samples planned for the research 5. Patient affiliated to Social Protection system 6. Informed consent form signed Exclusion Criteria: 1. Patient requiring surgery (for treatment of colon cancer or metastasis) 2. Patient with exclusive peritoneal carcinomatosis 3. Patient requiring radiotherapy 4. Patient unable to understand or comply with study instructions or requirements for psychological, family, social or geographical reasons 5. Pregnant and/ or breastfeeding women 6. Patient cared for an emergency context
Where this trial is running
Montpellier
- Institut Régional du cancer de Montpellier — Montpellier, France (RECRUITING)
Study contacts
- Study coordinator: Jean-Pierre Bleuse, MD
- Email: DRCI-icm105@icm.unicancer.fr
- Phone: 4 67 61 31 02
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Colon Cancer