Database for predicting cancer treatment response to cytokine therapy

Open Prospective Observational Cohort Study of the Effectiveness and Safety of Cytokinogenetic Therapy in Patients With Cancer Based on TCTD-1 Patient Registry

Observational OncoCareClinic 308 Ltd · NCT06222801

This study is trying to build a database to see how well cytokine therapy works for adults with cancer and what factors might influence their treatment outcomes.

Quick facts

Study typeObservational
Enrollment5000 (estimated)
Ages18 Years to 95 Years
SexAll
SponsorOncoCareClinic 308 Ltd Academic / other
Locations1 site (Moscow)
Trial IDNCT06222801 on ClinicalTrials.gov

What this trial studies

This observational study aims to create a comprehensive database to analyze the effectiveness and safety of cytokine therapy in cancer patients. It will collect extensive demographic, clinical, radiological, genetic, and laboratory data over a 10-year period to identify key factors influencing treatment outcomes. The study will focus on adult patients diagnosed with neoplasia who are eligible for cytokine therapy, aiming to develop and validate a predictive model for treatment response. By understanding the relationship between initial patient characteristics and therapy effectiveness, the study seeks to personalize treatment strategies.

Who should consider this trial

Good fit: Ideal candidates for this study are adult patients aged 18 years or older with a cancer diagnosis who are eligible for cytokine therapy.

Not a fit: Patients under 18 or over 95 years, those with hematologic cancers or thyroid tumors, and those with contraindications for cytokine therapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more personalized and effective treatment strategies for cancer patients undergoing cytokine therapy.

How similar studies have performed: While the approach of creating a predictive database is innovative, similar studies have shown promise in improving treatment personalization in oncology.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* adult patients aged 18 years or older with cancer who do not meet exclusion criteria, applied to the OncoCare308 Clinic Ltd. hospital for cytogenetic therapy, and are eligible to complete or have completed at least one course of cytogenetic therapy, as determined by the site.

Exclusion Criteria:

* Patients under 18 or over 95 years
* Patients with hematologic cancer or thyroid tumors
* Patients with contraindications for cytogenetic therapy
* Patients who die before the start of therapy or before the first course completeness
* Patients who do not sign the informed consent to be enrolled under the clinical observation in the hospital

Where this trial is running

Moscow

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions OncologyTNF-αTumor necrosis factor alphainterferon gammaIFN-γCancerCytokinogenetic therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.