Daily multivitamin/mineral supplements to improve metabolic, muscle, and mental health in midlife Asian women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind, placebo-controlled trial will give eligible midlife Asian women either a daily multivitamin/mineral (MVM) supplement or placebo for 12 months. Outcomes include change in MetaboAge and a range of metabolic, mental health, and musculoskeletal measures such as insulin sensitivity, mood scores, and muscle function. Participants are women aged 40–60 of Chinese, Malay, or Indian ethnicity with BMI 23–35 kg/m2, and those with major comorbidities or conflicting supplement use are excluded. The trial is conducted at the Institute for Human Development and Potential in Singapore and is designed to test whether improving micronutrient status can modify midlife health trajectories.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women aged 40-60 years old
* Chinese, Malay or Indian
* BMI between 23.0-35.0 kg/m2
* Proficient in English language
* Willing to comply with study protocol \& provide informed consent

Exclusion Criteria:

* Pregnant or planning a pregnancy
* Diagnosis with Diabetes, Polycystic Ovary Syndrome (PCOS), autoimmune diseases, chronic organ failure, severe heart disease, eating disorders and/or other medical conditions which in the PI's judgment which may affect study outcomes
* Fasting glucose value ≥ 7.0 mmol/L
* Active cancer or treatment of cancer in the last 3 years
* Participating in other nutritional intervention studies
* Taking oral corticosteroids, anti-psychotic and/or weight loss drugs
* Having planned hospitalization in the next 12 months
* Planning to have major diet changes in the next 12 months
* Taking a medically prescribed supplement(s) that contains 3 or more of the ingredients of the study product
* Taking a non-prescribed supplement(s) that contains 3 or more of the ingredients of the study product in the last 1 month

Where it's running

• Institute for Human Development and Potential (IHDP)
  Singapore, Singapore Recruiting

Study contacts

• Study coordinator: Johan Eriksson, MD
• Email: johan_eriksson@a-star.edu.sg
• Phone: 80616604

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.