Cytokine filtration in lung transplantation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of cytokine adsorption devices in lung transplantation to reduce early complications such as primary graft dysfunction (PGD). It is a randomized controlled trial comparing outcomes in patients receiving lung transplants with and without the cytokine filtration intervention. The goal is to gather preliminary data on the efficacy of this approach in improving patient survival and reducing complications associated with lung transplants. The study focuses on the inflammatory response that occurs immediately after transplantation and aims to mitigate its effects.

Why it matters

Who can join: the full rules

Inclusion Criteria:

• Eligibility to undergo double lung transplantation at either trial site

Exclusion Criteria:

1. Age \<18 years
2. Previous organ transplantation
3. Presence of any conditions at the time of surgery that require immunosuppressive therapy. Immunosuppressive therapy is defined as:

   1. Cyclosporine, Tacrolimus, Everolimus, or Sirolimus, minimum 1 month of treatment prior to transplantation and active treatment at the time of transplantation.
   2. Any form of antibody-based treatment that is known for having an immunomodulatory effect taken up to 1 week before transplantation.
4. Non-consent

Where it's running

• Sandra Lindstedt
  Lund, Skåne County, Sweden Recruiting

Study contacts

• Principal investigator: Sandra Lindstedt, MD, PhD — Skånes universitetssjukhus Lund
• Study coordinator: Sandra Lindstedt, MD,PhD
• Email: sandra.lindstedt_ingemansson@med.lu.se
• Phone: +46737220580

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Multimodal prospective approach to understand acute and chronic lung transplant rejection

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• Airway response to exercise after double lung transplant

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.