Culturally tailored food bundles and nutrition support for adults with food insecurity and diabetes

Culturally Tailored Program for Food-Insecure Adults With Type 2 Diabetes: The SPICE-D Study (Support for People Through Inclusive Cultural Eating for Diabetes)

Not applicable Interventional Wake Forest University Health Sciences · NCT07361341

This program will try culturally familiar food bundles and easy recipes to help adults with type 2 diabetes who have trouble affording healthy food.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment25 (estimated)
Ages18 Years and up
SexAll
SponsorWake Forest University Health Sciences Academic / other
Locations1 site (Winston-Salem, North Carolina)
Trial IDNCT07361341 on ClinicalTrials.gov

What this trial studies

This pilot hybrid study combines retrospective chart review with a prospective intervention and follow-up to examine the effects of culturally tailored food bundles and literacy-appropriate nutrition materials among predominantly Hispanic, low-income patients at a community clinic. Participants receive three months of culturally familiar food bundles, recipes, and cooking guides, with baseline data from charts and surveys plus follow-up surveys at 3 and 6 months. Outcomes include changes in HbA1c, blood pressure, body mass index, healthcare utilization, and qualitative feedback about food choices and diabetes self-management. The goal is to identify community-centered nutritional strategies that address structural and cultural barriers to healthy eating in uninsured patients served by the clinic.

Who should consider this trial

Good fit: Adults aged 18 or older who are active patients of the Community Care Clinic, meet the clinic's uninsured and low-income eligibility, have documented food insecurity screening and a diagnosis of type 2 diabetes or prediabetes, and live in the clinic's service area are ideal candidates.

Not a fit: People who are food-secure, already have stable diabetes control, or have medical conditions that prevent dietary changes may be unlikely to benefit from this food-bundle intervention.

Why it matters

Potential benefit: If successful, the intervention could improve diet, self-management, and metabolic control for food-insecure adults with diabetes and help reduce local health disparities.

How similar studies have performed: Previous food-support and medically tailored meal programs have produced improvements in diet quality and some metabolic measures, but culturally tailored interventions for low-income Hispanic communities are less extensively studied.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged ≥18 years at the time of the first clinic visit during the study period; regardless of sex, gender, race, or ethnicity
* Active patients of the Community Care Clinic (CCC) who received at least one clinical encounter between January 1, 2024 and December 31, 2024; with at least one scheduled follow-up appointment during the prospective study period
* Meet CCC's standard eligibility criteria: Uninsured status (no health insurance coverage); Family income ≤250% of the Federal Poverty Level; Resident of Forsyth County, North Carolina, or surrounding service area
* Completed at least one validated food insecurity screening tool during the study period as part of routine clinical care
* Medical record contains at least one documented measurement for any of the primary outcome variables (body mass index, blood pressure, HbA1c, or healthcare utilization metric)
* Documented diagnosis of Type 2 diabetes (ICD-10: E11.x) OR; Pre-diabetes diagnosis (ICD-10: R73.03) with a hemoglobin A1c ≥9.5%
* Reside within designated pickup/delivery zones for food bundle distribution (primary zip codes: 27101, 27105, 27107, and adjacent service areas)
* Able and willing to provide written informed consent (available in English and Spanish)
* Able to participate in baseline and follow-up assessments either in English or Spanish (the two primary languages at CCC)

Exclusion Criteria:

* Unable to speak proficiently in English or Spanish, as this study and the CCC staff are equipped only to provide services in English and Spanish languages.
* Have known food allergies (documented in the electronic medical record and/or self-reported to CCC or study staff) that may preclude participation in the food bundle program inherent to this protocol.
* Have incomplete records. Medical charts with missing or incomplete demographic information (age, gender) that cannot be verified through other sources
* Patients who were pregnant at any point during the study period (due to expected physiological changes in weight, blood pressure, and glucose metabolism that would confound outcome measurements)
* Patients with documented terminal illness or hospice care during the study period, as their health trajectory and care priorities differ fundamentally from the general population
* Transient patients. Patients who received only one-time urgent/emergent care without established continuity of care at CCC (defined as \<2 visits during study period)
* Type 1 diabetes (ICD-10: E10.x) - requires different dietary management; End-stage renal disease requiring dialysis (special dietary restrictions); Active eating disorder diagnosis; Severe food allergies that would limit ability to safely consume food bundle contents; Recent bariatric surgery (\<12 months)
* Documented cognitive impairment or intellectual disability that would impair ability to provide informed consent or participate meaningfully in intervention without caregiver support
* Currently enrolled in other intensive nutrition intervention studies or food prescription programs that would confound assessment of the intervention's independent effects
* Primary language other than English or Spanish
* Plans to move outside of CCC's service area or discontinue care at CCC within the 6-month study period
* Physical disabilities, literacy barriers, or other factors that would prevent completion of baseline or follow-up survey instruments, unless accommodations can be reasonably made

Where this trial is running

Winston-Salem, North Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Type 2 Diabetes Mellitustype 2 diabetes mellitusculturenutritionSpanishfood insecurity
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.