Clinical trial Recruiting at 4 sites Phase 2 Interventional Ages 12 and up

Culturally grounded parenting intervention for American Indian families

Official title: A Multiregional RCT of Parenting in 2 Worlds for Urban American Indian Families

Run by Arizona State University · NCT06324318 · Data updated 2026-11-12

This study tests a new parenting program designed for American Indian and Alaska Native families to see if it helps improve parenting skills and family life compared to a standard information program.

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Quick facts

PhasePhase 2
Study typeInterventional
Ages12 Years and up
SexAll
Enrollment360 (estimated)
SponsorArizona State University
Academic / other
Locations4 sites (Phoenix, Arizona and 3 other locations)
StatusRecruiting
StartedSeptember 14, 2023
Main results expectedMay 1, 2027
Study endsJune 1, 2028
Registry record updatedSeptember 8, 2026
Trial IDNCT06324318 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include American Indian parents or guardians of children aged 12 to 17 who reside in urban areas and attend urban schools.

Probably not a fit

Patients who do not identify as American Indian or whose children do not attend urban schools may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research tests the effectiveness of Parenting in 2 Worlds (P2W), a culturally grounded intervention aimed at American Indian/Alaska Native parents of adolescents in urban areas. The study compares P2W to an informational intervention, Healthy Families in 2 Worlds (HF2W), to assess improvements in parenting skills and family functioning. Conducted across four urban regions, the trial employs Community-based Participatory Research methods, involving local urban Indian centers in the implementation and delivery of the interventions. The study also examines how socioeconomic vulnerability and cultural identity influence the effectiveness of the interventions.

Why it matters

Potential benefit: If successful, this intervention could enhance parenting skills and reduce risky health behaviors among adolescents in American Indian families.

How similar studies have gone: Other studies have shown success with culturally tailored interventions for similar populations, indicating potential for positive outcomes in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Adult participants:

* Must be American Indian parents or guardians of American Indian children aged 12 to 17 who attend urban schools
* Must reside in the service areas of the four urban Indian centers who are participating in this study
* Self-identifies as American Indian
* Must be primary caregiver responsible for day-to-day decisions for an American Indian child ages 12 to 17

Child Participants:

* Aged 12 - 17
* Identified by their parent/guardian as American Indian
* Attends an urban school

Exclusion Criteria:

* Not applicable

Where it's running

  • Phoenix Indian Center
    Phoenix, Arizona, United States
    Recruiting
  • Denver Indian Center
    Denver, Colorado, United States
    Recruiting
  • Ain Dah Yung Center
    Saint Paul, Minnesota, United States
    Recruiting
  • Native American Community Services Erie and Niagara Counties
    Buffalo, New York, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.