CT-guided localization for small liver tumors before surgery
Official title: The Feasibility of CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection
Run by Northern Jiangsu People's Hospital · NCT05433467 · Data updated 2026-11-12
This study tests if using a special needle to pinpoint small liver tumors with CT scans before surgery can help doctors remove them more accurately for patients with cirrhosis.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 5 (estimated) |
| Sponsor | Northern Jiangsu People's Hospital Academic / other |
| Locations | 1 site (Yangzhou, Jiangsu) |
| Status | Recruiting |
| Started | May 1, 2022 |
| Main results expected | April 30, 2026 |
| Study ends | April 30, 2026 |
| Registry record updated | August 13, 2025 |
| Trial ID | NCT05433467 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 with a diagnosis of cirrhosis and micro hepatocellular carcinoma that cannot be detected by standard imaging methods.
✕Probably not a fit
Patients with advanced liver disease (Child-Pugh grade C) or significant uncontrolled health issues may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project aims to accurately locate micro hepatocellular carcinoma using CT guidance prior to surgical resection. By employing a specialized localization needle, the study seeks to enhance the precision of tumor removal, potentially reducing operation time and intraoperative bleeding. Patients with a preoperative diagnosis of cirrhosis and small liver tumors that are difficult to detect through standard imaging will be included. The localization process is performed on the day of surgery, ensuring that the surgical team has clear guidance for the procedure.
Why it matters
Potential benefit: If successful, this approach could lead to more effective surgical outcomes for patients with small liver tumors.
How similar studies have gone: While similar localization techniques have been explored, this specific approach using CT guidance for micro hepatocellular carcinoma is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Be at least 18 years old and give informed consent to participate in the study 2. A preoperative (clinical, radiological, or histological) diagnosis of cirrhosis of the liver due to any cause. 3. micro hepatocellular carcinoma (diameter less than 1cm). 4. Preoperative CT plain scan could not find the lesion, and preoperative B-ultrasound could not find the lesion. 5. Preoperative CT enhancement or MRI can detect the lesion. Exclusion Criteria: 1. Child-Pugh grade C 2. Uncontrolled Hypertension 3. Severe lung dysfunction 4. Severe cardiac dysfunction
Where it's running
-
Clinical Medical College, Yangzhou University
Yangzhou, Jiangsu, China Recruiting
Study contacts
- Study coordinator: Guo-Qing Jiang, MD
- Email: jgqing2003@hotmail.com
- Phone: +8651487373382
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.