CRP and early detection of leaking connections after GI surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the role of C-reactive protein in the early identification of anastomotic leakage following primary repair or anastomosis in adult GI surgeries. The study will monitor CRP levels in eligible patients and relate them to leakage outcomes while considering factors like nutrition, diabetes, smoking, and other risk variables. No intervention beyond standard care is described, and data will be analyzed to see if CRP trends can signal leakage sooner than current methods. Conducted at Sohag University, the study aims to clarify whether CRP testing could become a useful tool for earlier diagnosis and improved management. Results could inform clinicians about potential CRP thresholds or patterns associated with leakage risk.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Adult patients aged 18 years or older.
2. Patients having surgery for abdominal gastrointestinal disorders (esophageal- Gastric- small bowel -colon ) where a primary repair or anastomosis is performed such (pathological -traumatic )
3. Patients fit for surgery
4. Patients who provide informed written consent.

Exclusion Criteria:

1- Patients younger than 18 years. 2. Patients with pre-existing systemic infection or sepsis outside GIT 3. Patients with liver cirrhosis affecting CRP synthesis. 4. Patients receiving corticosteroids or immunosuppressive therapy. 5. Patients refusing participation in the study 6. Post operative wound infection

Where it's running

• Sohag University
  Sohag, Sohag Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Mahmoud Elsayed Hussein, resident
• Email: Mahmoud.hussin@med.sohag.edu.eg
• Phone: +201151575156

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.