Creating a questionnaire to assess cough control
Official title: The Development and Validation of a Cough Control Questionnaire
Run by King's College Hospital NHS Trust · NCT06918756 · Data updated 2026-11-12
This study is trying to create a new questionnaire to help people with chronic cough share how well their cough is controlled and see if treatments are working.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | King's College Hospital NHS Trust Academic / other |
| Locations | 1 site (London) |
| Status | Recruiting |
| Started | April 1, 2025 |
| Main results expected | September 1, 2031 |
| Study ends | September 1, 2031 |
| Registry record updated | April 9, 2025 |
| Trial ID | NCT06918756 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and over with chronic cough or acute cough who can read and write in English.
✕Probably not a fit
Patients who are current smokers, have had a respiratory infection recently, or are pregnant may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to develop a validated tool called the Cough Control Questionnaire (CCQ) to assess the control of chronic cough, which affects a significant portion of the population. The research will be conducted in three phases: first, a literature review of existing tools; second, the development of the CCQ through patient focus groups and expert reviews; and third, the validation of the CCQ with patients suffering from chronic cough. The goal is to create a patient-focused measure that can evaluate treatment benefits in clinical and research settings.
Why it matters
Potential benefit: If successful, this tool could improve the assessment and management of chronic cough, leading to better patient outcomes.
How similar studies have gone: While there are existing tools for other respiratory diseases, this approach to developing a dedicated cough control assessment is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients aged 18 and over with acute and chronic cough (including refractory chronic cough and unexplained chronic cough) and able to read and write in English. A smaller number (n =20) of healthy volunteers will also be included with no evidence of significant respiratory disease. Exclusion Criteria: * Current smokers (or smoking within the last 12 months), respiratory tract infection within the last 4 weeks, use of angiotensin converting enzyme inhibitors (ACEi), and pregnancy
Where it's running
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King's College Hospital
London, United Kingdom Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.