Creating a DNA bank for congenital heart disease in southeastern France
Creation of a French South-Eastern Database and DNA-bank of Congenital Heart Disease to Explore the Genetic Pathways
This study is creating a DNA bank for people with congenital heart defects in southeastern France to help understand the genetic causes of these conditions better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Sex | All |
| Sponsor | Assistance Publique Hopitaux De Marseille Academic / other |
| Locations | 1 site (Marseille) |
| Trial ID | NCT02923440 on ClinicalTrials.gov |
What this trial studies
This project aims to establish a comprehensive DNA bank specifically for patients with congenital heart defects in the south-eastern region of France. By collecting blood samples from affected individuals, the study seeks to enhance the understanding of the genetic pathways involved in these conditions. The initiative addresses the lack of local resources for genetic research and aims to facilitate better diagnosis and classification of congenital heart diseases. The study will utilize the existing infrastructure at the Assistance Publique Hopitaux de Marseille for sample collection and analysis.
Who should consider this trial
Good fit: Ideal candidates include newborns diagnosed with congenital heart defects who require a blood test as part of their medical care.
Not a fit: Patients who are pregnant or those unable to provide informed consent due to mental or physical incapacity may not benefit from this study.
Why it matters
Potential benefit: If successful, this initiative could lead to improved genetic understanding and management of congenital heart defects, ultimately benefiting affected patients.
How similar studies have performed: While similar DNA banks have been established in other regions, this specific initiative is novel for the south-eastern region of France.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Echocardiographic diagnosis of congenital heart defect falling within the classification Houyel and Bonnet * Necessity of making a blood test regardless of study * Medical care in the AP-HM Timone Hospital children, medical-surgical unit of pediatric and congenital cardiology, Marseille - These Parent Child Exclusion Criteria: * Pregnant women * Patients or parent / legal guardian (if minor) in physical or mental incapacity to understand or sign the consent * People in Emergencies * Persons deprived of freedom * Persons not beneficiaries of a social security scheme * Persons in health or social institution
Where this trial is running
Marseille
- Assistance Publique Hopitaux de Marseille — Marseille, France (Recruiting)
Study contacts
- Study coordinator: Caroline Ovaert
- Email: caroline.ovaert@ap-hm.fr
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.