Understanding the genetics of heterotaxy and congenital heart defects

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather specimens and data from individuals and their families affected by heterotaxy syndrome and related congenital heart defects. By performing genetic analyses, the study seeks to clarify the molecular genetics underlying these conditions, which are often genetic in nature. The collected medical information will help in understanding the symptoms, disease course, and potential management strategies for affected individuals. Ultimately, this research aims to enhance genetic counseling and contribute to the knowledge of normal and abnormal left-right anatomical development.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subjects with heterotaxy and related congenital heart defects
* Family members of subjects with heterotaxy and related congenital heart defects

Exclusion Criteria:

* Subjects without heterotaxy and related congenital heart defects
* Family members of subjects without heterotaxy and related congenital heart defects

Where it's running

• Indiana University School of Medicine
  Indianapolis, Indiana, United States Recruiting

Study contacts

• Principal investigator: Stephanie M. Ware, MD, PhD — Indiana University
• Study coordinator: Sarah K. Murphy, MPH
• Email: bankssk@iu.edu
• Phone: 317-278-3026

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.