Creating a database for sarcoma research
Official title: Development of a Monocentric and Prospective Clinical and Biological Database in Sarcoma
Run by Institut du Cancer de Montpellier - Val d'Aurelle · NCT04458792 · Data updated 2026-11-12
This study is creating a database to collect blood and tissue samples from people with liposarcoma to help researchers learn more about the disease and find new treatments.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 450 (estimated) |
| Sponsor | Institut du Cancer de Montpellier - Val d'Aurelle Academic / other |
| Locations | 1 site (Montpellier, Herault) |
| Status | Recruiting |
| Started | November 2016 |
| Main results expected | November 2027 |
| Study ends | November 2032 |
| Registry record updated | February 12, 2025 |
| Trial ID | NCT04458792 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 who have undergone surgery for sarcoma and are willing to provide blood samples.
✕Probably not a fit
Patients who are pregnant, under guardianship, or unable to comply with study requirements may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project aims to establish a clinical and biological database that collects blood and tissue samples from patients with sarcoma, specifically liposarcomas. The database will include clinical data to enhance understanding of sarcoma and facilitate the development of new treatments. By focusing on the Mdm2 gene and its role in liposarcoma, the study seeks to uncover insights that could lead to innovative therapeutic strategies. The collaboration with the U1194 INSERM unit will support ongoing research into various types of sarcomas.
Why it matters
Potential benefit: If successful, this initiative could lead to improved treatment options and outcomes for patients with sarcoma.
How similar studies have gone: While this approach is focused on a specific type of sarcoma, similar studies have shown promise in utilizing biological databases for cancer research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * men or women \> 18 years * Patient treated by surgery for : a primitive sarcoma and/or local relapse sarcoma and/or metastatic localisation of sarcoma * patient accepted blood sample * patient treated by radiotherapy before or after the surgery * Patient signed informed consent Exclusion Criteria: * Patient not affiliated to french Social Protection system * Patient under guardianship * Patient unable to understand or comply with study instructions or requirements for psychological, family, social or geographical reasons * Pregnancy and/or feeding * Patient take care in an Emergency Situation
Where it's running
-
Icm Val D'Aurelle
Montpellier, Herault, France Recruiting
Study contacts
- Study coordinator: Aurore MOUSSION
- Email: DRCI-icm105@icm.unicancer.fr
- Phone: 4 67 61 31 02
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
MIGHTY: CAR T cells targeting B7-H3 for pediatric, teen, and young adult sarcoma
This Phase 1 trial tests autologous hBRCA84D CAR T cells in kids, teens, and young adults (1–24) with relapsed or refractory RMS, ES, or DSRCT to see if the therapy is feasible and safe.
-
Lifileucel (Tumor-infiltrating lymphocytes) for advanced soft tissue sarcoma
This study tests lifileucel, a cell therapy made from a patient’s own tumor cells, in adults with unresectable or metastatic soft tissue sarcoma who have had prior treatments to see if it helps shrink tumors and improve outcomes.
-
Domatinostat with Sirolimus for relapsed or refractory sarcoma and osteosarcoma
This study tests whether the cancer drugs domatinostat and sirolimus together can help adolescents and adults whose sarcoma or osteosarcoma has come back or stopped responding to standard therapy.
-
Clonal Hematopoiesis Effects with Chemo and Radiation in Solid Cancers
This study tests whether clonal hematopoiesis affects outcomes for adults with solid cancers who are receiving chemotherapy or radiation.
-
AYA Sarcoma Survivors: Personalized Exercise Program Pilot
This pilot tests a personalized 12-week exercise program for adolescents and young adults with sarcoma to see if a triage tool can connect them with the right rehabilitation and exercise services.
-
Fluorescence-guided surgery to reduce unexpected positive margins in high-grade sarcoma
This phase II trial tests whether adding fluorescence-guided surgery with indocyanine green can lower unexpected positive margins in patients with high-grade sarcoma compared to standard surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.