Creatine and intradialytic exercise in people on hemodialysis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind trial compares four groups to assess the independent and combined effects of creatine monohydrate supplementation and an intradialytic exercise program over 8 weeks in adults undergoing thrice-weekly hemodialysis. Participants are assigned to standard care, creatine only, intradialytic exercise only, or creatine plus exercise. Outcomes include body composition, biochemical markers, and measures of functional capacity at baseline and after 8 weeks. The study aims to inform strategies to improve nutritional status, physical function, and overall health in CKD patients receiving dialysis. Safety monitoring includes tracking adverse events related to creatine and exercise tolerance.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* atients who are treated at the State Haemodialysis Centre.

  * Patients who receive haemodialysis three times a week.
  * Signature of informed consent.
  * Patients over 18 years of age, both men and women.
  * Patients who have been on haemodialysis for no more than two years.

Exclusion Criteria:

Patients who have had a limb amputated.

* Patients who are in a state of anuria.
* Inability to perform muscular resistance or aerobic resistance exercises.
* Patients unable to perform physical exercise.
* HIV-positive patients. Elimination.
* Patients who voluntarily withdraw from the project.
* Inability to perform physical exercise.
* Death.
* Adverse events related to creatine consumption.

Where it's running

• IMSS-Bienestar State Haemodialysis Centre
  Colima, Coliima, Mexico Recruiting

Study contacts

• Study coordinator: Israel Pérez Palafox PALAFOX Master of Medical Sciences
• Email: iperez@ucol.mx
• Phone: +523151260402

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.