Clinical trial Recruiting at 1 site Interventional Ages 18 and up Women only

CRAFT-G: a remote group program to help brain function after breast cancer

Official title: The Computerized Retraining and Functional Treatment: Effectiveness-implementation Hybrid Trial of Group Teleintervention Among Breast Cancer Survivors With Cognitive Impairment

Run by Hadassah Medical Organization · NCT07591857 · Data updated 2026-11-12

A remotely delivered group program called CRAFT-G tests whether group cognitive retraining and functional strategies can help breast cancer survivors with cognitive symptoms feel and function better.

Quick facts

Study typeInterventional
Ages18 Years and up
SexWomen only
Enrollment48 (estimated)
SponsorHadassah Medical Organization
Academic / other
Locations1 site (Jerusalem)
StatusRecruiting
StartedNovember 16, 2025
Main results expectedOctober 2027
Study endsJune 2028
Registry record updatedMay 18, 2026
Trial IDNCT07591857 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Women 18 years or older with subjective and objective cognitive concerns after breast cancer treatment, 6 months or more post-treatment, with internet access and basic computer skills.

Probably not a fit

Individuals without cognitive concerns, without internet access, or with unstable psychiatric/health conditions may see little or no benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional trial tests a tele-rehabilitation group intervention (CRAFT-G) combining computerized cognitive training with CO-OP-based goal setting and psychoeducation for breast cancer survivors experiencing cancer-related cognitive impairment. Participants join six remote 1.5-hour group sessions led by an occupational therapist and complete weekly cognitive training via an app. The study will compare CRAFT-G to a waitlist control, with crossover after six weeks, and will also collect data on barriers and facilitators to implementation in real-world settings. Outcomes include cognitive function, mental health, and daily functioning, with a follow-up assessment three months after treatment ends.

Why it matters

Potential benefit: If successful, participants may experience improved thinking, mood, and ability to perform daily activities.

How similar studies have gone: Previous work on CRAFT showed feasibility and benefit for CRCI; this trial extends it to a telemedicine, group-format and real-world implementation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. women, 18 years old and older
2. A subjective concern about declines in cognitive functioning related to a diagnosis of breast cancer and/or cancer related treatment
3. Objective cognitive decline with no dementia (19\<MOCA)
4. 6 months or more after completion of an active treatment for cancer
5. Daily access to the internet and sufficient basic skills to operate a computer

Exclusion Criteria:

* Unstable psychiatric or other health condition according to participants' self-report and medical file.

Where it's running

  • Hadassah Medical Care
    Jerusalem, Israel
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.