CRAFT-G: a remote group program to help brain function after breast cancer
Official title: The Computerized Retraining and Functional Treatment: Effectiveness-implementation Hybrid Trial of Group Teleintervention Among Breast Cancer Survivors With Cognitive Impairment
Run by Hadassah Medical Organization · NCT07591857 · Data updated 2026-11-12
A remotely delivered group program called CRAFT-G tests whether group cognitive retraining and functional strategies can help breast cancer survivors with cognitive symptoms feel and function better.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 48 (estimated) |
| Sponsor | Hadassah Medical Organization Academic / other |
| Locations | 1 site (Jerusalem) |
| Status | Recruiting |
| Started | November 16, 2025 |
| Main results expected | October 2027 |
| Study ends | June 2028 |
| Registry record updated | May 18, 2026 |
| Trial ID | NCT07591857 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women 18 years or older with subjective and objective cognitive concerns after breast cancer treatment, 6 months or more post-treatment, with internet access and basic computer skills.
✕Probably not a fit
Individuals without cognitive concerns, without internet access, or with unstable psychiatric/health conditions may see little or no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional trial tests a tele-rehabilitation group intervention (CRAFT-G) combining computerized cognitive training with CO-OP-based goal setting and psychoeducation for breast cancer survivors experiencing cancer-related cognitive impairment. Participants join six remote 1.5-hour group sessions led by an occupational therapist and complete weekly cognitive training via an app. The study will compare CRAFT-G to a waitlist control, with crossover after six weeks, and will also collect data on barriers and facilitators to implementation in real-world settings. Outcomes include cognitive function, mental health, and daily functioning, with a follow-up assessment three months after treatment ends.
Why it matters
Potential benefit: If successful, participants may experience improved thinking, mood, and ability to perform daily activities.
How similar studies have gone: Previous work on CRAFT showed feasibility and benefit for CRCI; this trial extends it to a telemedicine, group-format and real-world implementation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. women, 18 years old and older 2. A subjective concern about declines in cognitive functioning related to a diagnosis of breast cancer and/or cancer related treatment 3. Objective cognitive decline with no dementia (19\<MOCA) 4. 6 months or more after completion of an active treatment for cancer 5. Daily access to the internet and sufficient basic skills to operate a computer Exclusion Criteria: * Unstable psychiatric or other health condition according to participants' self-report and medical file.
Where it's running
-
Hadassah Medical Care
Jerusalem, Israel Recruiting
Study contacts
- Study coordinator: Chenanit Hamami
- Email: chenanit.hamami@mail.huji.ac.il
- Phone: +972506373099
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.