Prolonged nightly fasting to improve sleep and cognition in breast cancer survivors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot randomized controlled trial investigates the effects of an 8-week prolonged nightly fasting (PNF) intervention on cognitive function, sleep quality, and overall health-related quality of life in breast cancer survivors experiencing cancer-related cognitive impairment. Participants will be randomly assigned to either the PNF group or a Health Education-Only control group, with both groups receiving health education throughout the study. The trial aims to assess the feasibility of the PNF intervention and its impact on various health outcomes among a diverse population of breast cancer survivors across the United States.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. ≥18 years old
2. diagnosed with breast cancer (all stages included)
3. ≥3 months post neoadjuvant or adjuvant chemotherapy (maintenance or palliative systemic therapy is included)
4. score ≤30 or lower on the Patient Reported Outcome Measurement Information System Cognitive Function Short Form 8a (sr-CRCI)
5. able to speak/understand English
6. have access to a computer and Wi-Fi
7. live within the United States
8. Identifies as female
9. willing and able to fully participate in the study

Exclusion Criteria:

1. type 1 diabetes
2. actively enrolled in formal diet/weight loss program
3. previous bariatric surgery
4. eating disorder history
5. night shift work
6. pregnant, breast feeding, or trying to get pregnant
7. dementia, psychological, psychiatric, or neurological diagnoses
8. active brain or central nervous system disease
9. prior or current use of memory enhancing medications
10. history or current brain radiation
11. frequently fasting for 12+ hours every night

13\) history of hypoglycemia 14) depression screening on PHQ9 with a score of 20 or greater across all 9 questions OR anything other than 0 on question 9

Where it's running

• Arizona State University
  Phoenix, Arizona, United States Recruiting

Study contacts

• Principal investigator: Dorothy Sears, PhD — Arizona State University
• Study coordinator: Jen Project Coordinator
• Email: restorestudy@asu.edu
• Phone: 602-496-8248

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.