Couple-based physical activity program for patients and caregivers
Mates in Motion: Feasibility and Acceptability of a Couple-Based Physical Activity Intervention
This study is testing a program called Mates in Motion to see if it helps patients undergoing certain cancer treatments and their caregivers become more physically active together.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 130 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mayo Clinic Academic / other |
| Drugs / interventions | chimeric antigen receptor, CART |
| Locations | 1 site (Scottsdale, Arizona) |
| Trial ID | NCT06073951 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of a couple-based physical activity intervention called Mates in Motion for patients undergoing hematopoietic cell transplantation (HCT) or chimeric antigen receptor T-cell therapy (CART) and their caregivers. The program focuses on training couples in communication skills and behavior change techniques to support each other in becoming more physically active. Participants are randomized into two groups: one receives the intervention with weekly sessions and support, while the other group receives usual care. The study aims to assess feasibility, acceptability, and changes in physical activity, endurance, and overall health among the dyads over an 8-week period.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older who are scheduled for HCT or CART and are in a committed relationship with a caregiver.
Not a fit: Patients who are not in a committed relationship or those unable to participate in a walking program may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could enhance physical activity levels and overall health for patients and their caregivers during critical treatment periods.
How similar studies have performed: While couple-based interventions are gaining traction, this specific approach in the context of HCT and CART is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * PATIENTS: Age 18 years or older * PATIENTS: Scheduled to receive an autologous or allogeneic hematopoietic cell transplant (HCT) or chimeric antigen receptor (CAR)-T cell therapy * PATIENTS: Able to speak and comprehend English * PATIENTS: Being married or in a committed (self-defined) cohabiting same- or opposite-sex relationship * PATIENTS: Physician-approved for a walking program * CAREGIVERS: Age 18 years or older * CAREGIVERS: Able to speak and comprehend English * CAREGIVERS: Married to or in a committed, cohabiting, same- or opposite-sex relationship with the patient * CAREGIVERS: Able to participate in a walking program Exclusion Criteria: * None per se beyond the converse of the inclusions listed above, for example, age younger than 18 years and non-partnered
Where this trial is running
Scottsdale, Arizona
- Mayo Clinic in Arizona — Scottsdale, Arizona, United States (Recruiting)
Study contacts
- Principal investigator: Nandita Khera, MD, MPH — Mayo Clinic
- Study coordinator: Clinical Trials Referral Office
- Email: mayocliniccancerstudies@mayo.edu
- Phone: 855-776-0015
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.