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Clinical trial No longer in our active list Interventional Ages 18 and up

Couple-based physical activity program for patients and caregivers

Official title: Mates in Motion: Feasibility and Acceptability of a Couple-Based Physical Activity Intervention

Run by Mayo Clinic · NCT06073951 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing a program called Mates in Motion to see if it helps patients undergoing certain cancer treatments and their caregivers become more physically active together.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment130 (estimated)
SponsorMayo Clinic
Academic / other
Drugs / interventionschimeric antigen receptor, CART
Locations1 site (Scottsdale, Arizona)
Trial IDNCT06073951 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older who are scheduled for HCT or CART and are in a committed relationship with a caregiver.

Probably not a fit

Patients who are not in a committed relationship or those unable to participate in a walking program may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of a couple-based physical activity intervention called Mates in Motion for patients undergoing hematopoietic cell transplantation (HCT) or chimeric antigen receptor T-cell therapy (CART) and their caregivers. The program focuses on training couples in communication skills and behavior change techniques to support each other in becoming more physically active. Participants are randomized into two groups: one receives the intervention with weekly sessions and support, while the other group receives usual care. The study aims to assess feasibility, acceptability, and changes in physical activity, endurance, and overall health among the dyads over an 8-week period.

Why it matters

Potential benefit: If successful, this intervention could enhance physical activity levels and overall health for patients and their caregivers during critical treatment periods.

How similar studies have gone: While couple-based interventions are gaining traction, this specific approach in the context of HCT and CART is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* PATIENTS: Age 18 years or older
* PATIENTS: Scheduled to receive an autologous or allogeneic hematopoietic cell transplant (HCT) or chimeric antigen receptor (CAR)-T cell therapy
* PATIENTS: Able to speak and comprehend English
* PATIENTS: Being married or in a committed (self-defined) cohabiting same- or opposite-sex relationship
* PATIENTS: Physician-approved for a walking program
* CAREGIVERS: Age 18 years or older
* CAREGIVERS: Able to speak and comprehend English
* CAREGIVERS: Married to or in a committed, cohabiting, same- or opposite-sex relationship with the patient
* CAREGIVERS: Able to participate in a walking program

Exclusion Criteria:

* None per se beyond the converse of the inclusions listed above, for example, age younger than 18 years and non-partnered

Where it's running

  • Mayo Clinic in Arizona
    Scottsdale, Arizona, United States     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.