Correcting crossbites in young children

The Effect of Timing on Lateral Crossbite Correction - a Randomized Study

Not applicable Interventional University of Oulu · NCT03353766

This study is testing whether fixing crossbites early in young children using a special appliance helps them more than waiting until their adult teeth come in.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages5 Years to 18 Years
SexAll
SponsorUniversity of Oulu Academic / other
Locations1 site (Oulu)
Trial IDNCT03353766 on ClinicalTrials.gov

What this trial studies

This longitudinal investigation aims to evaluate the long-term effects of early correction of lateral crossbites using a Quad-Helix appliance in children aged 5 to 6 years. The study compares outcomes of early treatment with those who receive treatment after the eruption of their first permanent molars. Children with specific malocclusions are screened and randomized into two groups to assess treatment efficacy, total orthodontic time, and patient compliance. The research seeks to provide insights into the benefits and burdens of early orthodontic intervention.

Who should consider this trial

Good fit: Ideal candidates are children aged 5 to 6 years with crossbites involving at least two deciduous lateral teeth.

Not a fit: Patients with anterior crossbites, missing permanent teeth, or craniofacial syndromes will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved orthodontic outcomes and reduced treatment times for children with crossbites.

How similar studies have performed: While there is limited randomized controlled trial data on early orthodontic treatments, similar approaches have shown promise in improving outcomes for malocclusions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Crossbite of at least two deciduous lateral teeth
* Full deciduous dentition
* Age 5 to 6 years

Exclusion Criteria:

* Anterior crossbite
* Missing permanent teeth,
* Craniofacial syndrome, Cleft lip/palate

Where this trial is running

Oulu

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions MalocclusionCrossbiteEarly Orthodontic treatmentOrthodontic treatment outcomeCrossbite treatment
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.