Clinical trial Recruiting at 1 site Interventional Ages 18 to 30

Core stability versus cognitive training to improve balance and postural control in chronic ankle instability

Official title: Effect of Adding Functional Core Stability Training or Cognitive Training on Balance and Postural Control in Rehabilitation of Chronic Ankle Instability

Run by Cairo University · NCT07283276 · Data updated 2026-11-12

This project will test whether dynamic core stability exercises or cognitive (dual-task) training help adults with chronic ankle instability improve balance, postural control, and reduce feelings of giving way.

Quick facts

Study typeInterventional
Ages18 Years to 30 Years
SexAll
Enrollment45 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedAugust 15, 2025
Main results expectedFebruary 1, 2026
Study endsMarch 1, 2026
Registry record updatedDecember 15, 2025
Trial IDNCT07283276 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18–30 with unilateral chronic lateral ankle sprain/instability for at least 6 months (≥2 episodes), a validated ankle instability score above the threshold, and BMI under 30.

Probably not a fit

Patients with recent or prior spine/pelvis/lower-extremity fracture, surgery, acute lower-extremity injury, or current low back pain requiring medical or surgical care, as well as those outside the specified age/BMI criteria, are unlikely to qualify or benefit from these interventions.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with unilateral chronic ankle instability will be assigned to receive dynamic functional core stability exercises, cognitive (dual-task) training, or a combined program delivered in outpatient sessions. The program includes strengthening, balance, spinal motor control (stabilization) exercises, and cognitive tasks tailored to dual-task conditions. Outcomes measured before and after the intervention include balance and postural control tests, functional performance, ankle dorsiflexion range of motion, self-reported ankle instability scores, and mental workload. The study compares changes in single- and dual-task performance to determine which approach best improves stability and reduces re-injury risk.

Why it matters

Potential benefit: If successful, the intervention could improve balance and postural control and reduce episodes of instability for people with chronic ankle instability.

How similar studies have gone: Previous studies of core stability and dual-task (cognitive) training have shown improvements in postural control and joint position sense in chronic ankle instability, though combining dynamic core and cognitive training is a more recent approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Inclusion criteria will be based on the standard criteria outlined by the International Ankle Consortium

1. History of chronic lateral ankle sprain and/or recurrent sprain and/or "feelings of instability or giving way" for 6 months or more before the study, with at least 2 episodes.
2. Patients are between 18 and 30 years old. 3- Body mass index less than 30

4\. The patient has a history of at least one significant ankle sprain with associated inflammatory symptoms and at least one day of interrupted physical activity.

5\. Patients who have unilateral chronic ankle instability. 6. Self-reported ankle instability should be confirmed using a validated ankle instability questionnaire (greater than 24).

Exclusion Criteria:

Those with a history of spine, pelvis, and lower extremity injury, fracture, or surgery 2- Those with low back pain that require medical or surgical intervention. 3- Having a history of an acute lower extremity injury or lower extremity surgery or fracture in the 3 months before the Study 4. Participation in formal ankle rehabilitation in the 3 months before the study.

5\. Being diagnosed with neurologic dysfunction, such as multiple sclerosis, Parkinson's disease, or head injury

Where it's running

  • out-patient clinic, faculty of physical therapy, Cairo university
    Cairo, Egypt
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.