Coordinated diet and exercise program for adults with cystic fibrosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the impact of a coordinated dietetic-adapted physical activity program on increasing lean body mass in adults with cystic fibrosis who are being treated with Elexacaftor-Tezacaftor-Ivacaftor. The program aims to address malnutrition and improve muscle function through tailored dietary adjustments and physical activity. Participants will be monitored for changes in body composition and respiratory function over the course of the intervention. The study is multicenter and randomized, ensuring a diverse participant pool and robust data collection.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subject aged 18 or over
* Suffering from cystic fibrosis
* Treated with Elexacaftor-Tezacaftor-Ivacaftor for at least 6 months
* Affiliated to a social security scheme
* with a signed Informed Consent form.

Exclusion Criteria:

* Pregnant and breast-feeding women
* Subject under legal protection, guardianship or curatorship
* Subject whose physical activity is not medically authorised or whose physical and motor capacities do not allow them to take part in physical activity.
* Subject who is unable to comply with the requirements of the DIAPASOM program
* Difficulty in understanding the self-questionnaires
* Wearing a pacemaker or metal prosthesis
* Fluid retention

Where it's running

• Cystic Fibrosis Resource and Competence Centre, University Hospital, Angers
  Angers, France Recruiting
• Cystic Fibrosis Resource and Competence Centre, Fondation Ildys, Roscoff
  Roscoff, France Recruiting
• Cystic Fibrosis Resource and Competence Centre, University Hospital, Tours
  Tours, France Recruiting
• Cystic Fibrosis Resource and Competence Centre, Hospital, Tours
  Vannes, France Recruiting

Study contacts

• Principal investigator: Julie MANKIKIAN, MD — University Hospital, Tours
• Study coordinator: Amelie GIBORY
• Email: a.gibory@chu-tours.fr
• Phone: 0247474747

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.