Continuous glucose monitoring plus AI video coaching for adults with prediabetes
Official title: Continuous Glucose Monitoring (CGM) in Prediabetes With Health Education Videos
Run by University of Southern California · NCT07477249 · Data updated 2026-11-12
This project will try combining a wearable continuous glucose monitor with daily AI-generated education videos to see if it helps adults with prediabetes improve their blood sugar over 20 days.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 35 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | University of Southern California Academic / other |
| Locations | 1 site (Los Angeles, California) |
| Status | Recruiting |
| Started | February 26, 2026 |
| Main results expected | March 30, 2027 |
| Study ends | March 30, 2027 |
| Registry record updated | March 30, 2026 |
| Trial ID | NCT07477249 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 35 or older in Los Angeles County with prediabetes (finger-prick A1c or fasting glucose) who can wear a CGM, use a compatible smartphone, and read English or Spanish are ideal candidates.
✕Probably not a fit
People with diagnosed diabetes, pregnancy, medical conditions that affect glucose, incompatible smartphones, prior participation in CGM studies, or planned travel outside California during the study are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This Phase 0 intervention development project will enroll 50 English- and/or Spanish-speaking adults aged 35 and older from Los Angeles County with non-clinical prediabetes confirmed by a finger-prick A1c or fasting glucose. Participants will wear a CGM device for 20 days, with glucose data masked for the first 10 days and unmasked for the next 10 days. During the unmasked phase participants will receive daily short health-education videos generated by AI on their smartphones, and the study will compare the duration of glucose excursions between masked and unmasked phases. Recruitment is community-based through the Southern California Center for Latino Health and outcomes will focus on short-term glucose regulation and feasibility.
Why it matters
Potential benefit: If successful, this approach could help people with prediabetes reduce glucose spikes and slow or prevent progression to type 2 diabetes.
How similar studies have gone: Previous pilot work has shown CGM feedback can change behavior and reduce post-meal glucose in at-risk individuals, but pairing CGM with daily AI-generated education videos is relatively novel and not widely tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 35 years of age or older * Willingness to wear CGM sensor * Prediabetes by finger prick blood A1C% or fasting glucose * Centers for Disease Control and Prevention (CDC) prediabetes risk test score of 5 or higher or recent prediabetes diagnosis from physician Exclusion Criteria: * Diagnosed with any disorder that interferes with glucose * Influential medical disorder/event affecting ability to participate in study * Incompatible smartphone device not pairing with Dexcom G6 app * Currently pregnant * Previously participated in other Continuous Glucose Monitoring studies * Having a planned trip outside California in the following 2 months
Where it's running
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Southern California Center for Latino Health (SCCLH)
Los Angeles, California, United States Recruiting
Study contacts
- Principal investigator: David S Black, PhD MPH — University of Southern California Keck School of Medicine
- Study coordinator: David S Black, PhD MPH
- Email: davidbla@usc.edu
- Phone: 3234428223
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.