Conox-guided anesthesia for children having adenotonsillectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial will enroll 128 children aged 3-12 with ASA I-II who are scheduled for elective adenotonsillectomy and randomize them to Conox-guided anesthesia or standard monitoring. Conox is a non-invasive EEG device that provides qCON (hypnosis) and qNOX (nociception) indices to guide anesthetic and analgesic dosing alongside routine monitoring. All participants will receive a standardized anesthesia protocol (propofol, fentanyl, rocuronium induction; sevoflurane maintenance) and the primary outcome is total intraoperative opioid consumption. Secondary outcomes include emergence time, extubation time, postoperative agitation, pain scores, and correlations between qCON/qNOX values and hemodynamic measures.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Children aged 3 to 12 years ASA physical status I-II Scheduled for elective adenotonsillectomy No acute infection or systemic disease Parent or legal guardian able to provide written informed consent

Exclusion Criteria:

Skin lesions or anatomical abnormalities preventing placement of EEG electrodes History of neurological disease, including epilepsy or neurological syndromes Body mass index above the 95th percentile for age Previous pharyngeal surgery History of anesthesia-related complications Absence of written informed consent from a parent or legal guardian

Where it's running

• Kayseri Şehir Hastanesi
  Kayseri, Turkey (Türkiye) Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.