Concomitant TURP with bladder stone surgery vs bladder stone surgery alone in men with BPH
Official title: Impact of Concomitant Transurethral Resection of the Prostate on Postoperative Outcomes of Bladder Stone Surgery and Predictors of Subsequent TURP: A Prospective Comparative Study
Run by Beni-Suef University · NCT07831486 · Data updated 2026-11-12
This study tests whether adding TURP at the time of bladder stone surgery helps men with BPH have better short-term outcomes.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years and up |
| Sex | Men only |
| Enrollment | 104 (estimated) |
| Sponsor | Beni-Suef University Academic / other |
| Locations | 1 site (Banī Suwayf, Beni Suweif Governorate) |
| Status | Recruiting |
| Started | October 2026 |
| Main results expected | April 2028 |
| Study ends | July 2028 |
| Registry record updated | September 21, 2026 |
| Trial ID | NCT07831486 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are men 40+ with symptomatic BPH (IPSS ≥8), prostate size ≥30 g, Qmax ≤15 mL/s, and imaging-confirmed bladder stones.
✕Probably not a fit
Patients with active UTI, prior prostate/bladder surgery, urethral stricture, or suspected cancer may not benefit from this strategy.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective randomized, single-center study enrolling men aged 40 and older with BPH and bladder stones. Participants are assigned to either cystolitholapaxy alone or cystolitholapaxy with simultaneous TURP. Preoperative evaluations include IPSS, PSA, urine tests, imaging, and uroflowmetry; follow-ups at 1, 3, and 6 months assess stone-free rate, recurrence, and functional outcomes. The trial aims to identify predictors for delaying TURP if stone surgery is chosen first. The setting is the Urology Department at Beni-Suef University, and 104 participants are planned.
Why it matters
Potential benefit: If successful, this approach could improve stone clearance and reduce the need for subsequent procedures in men with BPH-related bladder stones.
How similar studies have gone: There is limited evidence on single-stage vs. staged treatment for bladder stones with concomitant TURP; this study addresses a gap with randomized design.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult men aged 40 years or older. * Lower urinary tract symptoms (LUTS) attributed to benign prostatic hyperplasia (BPH). * International Prostate Symptom Score (IPSS) \>= 8. * Prostate size \>= 30 grams (measured by ultrasonography). * Maximum urinary flow rate (Qmax) \<= 15 mL/s. * Presence of urinary bladder calculus/calculi confirmed by diagnostic imaging. * Written informed consent provided prior to study enrollment. Exclusion Criteria: * Evidence or history of urethral stricture. * Known or suspected prostate cancer. * Known or suspected bladder cancer / urothelial malignancy. * Neurogenic bladder dysfunction. * Chronic urinary retention with overflow incontinence. * Previous prostate or bladder neck surgery (e.g., prior TURP, TUIP, open prostatectomy). * Active urinary tract infection (UTI) at the time of surgery (patients treated for infection preoperatively may be reassessed for eligibility).
Where it's running
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Faculty of Medicine, Beni-Suef University
Banī Suwayf, Beni Suweif Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Mahmoud Abdallah Mahmoud, lecturer of urology
- Email: mahmoud.abdalla@med.bsu.edu.eg
- Phone: 01155361979
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.