Comparing Zoledronic Acid with and without Vitamin D for Osteoporosis
Examination of Bone Metabolism and Bone Mineral Density by Zoledronic Acid in Primary and Secondary Osteoporosis
This study tests if adding vitamin D to Zoledronic acid can help people with osteoporosis improve their bone health better than just using Zoledronic acid alone.
Quick facts
| Phase | Phase 2 |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | Shinshu University Academic / other |
| Locations | 1 site (Matsumoto, Nagano) |
| Trial ID | NCT03183557 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the efficacy of Zoledronic acid alone versus Zoledronic acid combined with active vitamin D in patients with primary and secondary osteoporosis. The study will involve osteoporotic patients who are interested in receiving treatment with Zoledronic acid. By comparing these two treatment approaches, the trial seeks to determine if the addition of vitamin D enhances the effectiveness of Zoledronic acid in improving bone health. The trial is designed as a Phase 2 interventional study.
Who should consider this trial
Good fit: Ideal candidates for this study are osteoporotic patients who are willing to take Zoledronic acid.
Not a fit: Patients who are allergic to Zoledronic acid or vitamin D, pregnant or breastfeeding, or who have not taken Zoledronic acid in the last two years may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective treatment option for patients with osteoporosis.
How similar studies have performed: There is limited comparative data available on the efficacy of Zoledronic acid combined with active vitamin D, making this approach relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Osteoporotic patients who want to take zoledronic acid Exclusion Criteria: * Patients who are allergic to zoledronic acid or vitamin D * Patients who are pregnant or breast-feeding * Patients who have not taken zoledronic acid for the last 2 years
Where this trial is running
Matsumoto, Nagano
- Yukio Nakamura — Matsumoto, Nagano, Japan (Recruiting)
Study contacts
- Study coordinator: Yukio Nakamura, MD, PhD
- Email: yxn14@aol.jp
- Phone: +81-263-37-2659
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.