Comparing yoga therapy and physiotherapy for moderate axial spondyloarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of yoga therapy compared to traditional physiotherapy in patients with moderate axial spondyloarthritis (axSPA). It aims to assess improvements in physical symptoms such as pain and stiffness, as well as psychological aspects like anxiety and fatigue. Participants will be randomly assigned to either yoga therapy or physiotherapy, with outcomes measured over a specified period. The study seeks to provide evidence for non-drug therapeutic approaches in managing axSPA.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* French-speaking patient aged 18 and over
* Patient with axial spondyloarthritis (axSPA) according to Assessment of SpondyloArthritis International Society, diagnosed by a rheumatologist
* "Moderately active" to "active" form of axSPA (basic BASDAI \> 3)
* Stable disease: No recent or foreseeable introduction in the next 6 months of drug treatments for axSPA (excluding analgesics)
* Absence of disabling stress urinary incontinence
* Geographical or organizational possibility of undergoing the study
* Patient informed and having signed the informed consent form for participation in the research

Exclusion Criteria:

* Pregnancy or breastfeeding
* Recent childbirth (within the last six months)
* Patient already practicing yoga or having practiced it in the last six months
* Abdominal or spinal surgery in the last six months
* Motor neurological deficit
* Sphincter deficit
* Any other somatic pathology preventing the practice of physiotherapy or yogatherapy according to the opinion of the evaluating clinician
* Depressive syndrome requiring specific treatment
* Non-affiliation to a social security scheme (beneficiary or beneficiary) or to another social protection scheme
* Patient deprived of liberty by judicial or administrative decision or under legal protection (guardianship, safeguard of justice)
* Currently participating in or in a period of exclusion from: another interventional research involving human participants, a clinical trial on a medical product for human, a clinical investigation on a medical device. Participation in non-interventional research is authorized.

Where it's running

• Hôpital Avicenne
  Bobigny, France Recruiting
• Hôpital Henri Mondor
  Créteil, France Recruiting
• Hôpital Cochin
  Paris, France Recruiting
• Hôpital Henri Mondor
  Créteil, France Active not recruiting
• Hôpital Pitié Salpetrière
  Paris, France Active not recruiting

Study contacts

• Study coordinator: Petra PAREJO MARGALLO
• Email: petri.parejo-margallo@aphp.fr
• Phone: +33 1 40 27 43 13

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Oral ERAP1 blocker GRWD0715 for axial spondyloarthritis (EAST-1)

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• Observational cohort for early spondyloarthritis in Germany

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  Recruiting Charite University, Berlin, Germany · Berlin · NCT01277419

• FAPI‑74 PET/CT versus FDG PET/CT for inflammation in FUO, IgG4‑RD, and axial spondyloarthritis

  This project will test whether [18F]-AlF-FAPI-74 PET/CT finds inflammation more accurately than standard [18F]-FDG PET/CT in people with fever of unknown origin, IgG4‑related disease, or axial spondyloarthritis.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.