Comparing yoga therapy and physiotherapy for moderate axial spondyloarthritis

Effects of Yoga Therapy in Rehabilitation Compared to Physiotherapy in Moderate Axial Spondyloarthritis (axSPA): a Randomized Controlled Multicenter Study.

Not applicable Interventional Assistance Publique - Hôpitaux de Paris · NCT06083090

This study is testing whether yoga therapy can help people with moderate axial spondyloarthritis feel better compared to traditional physiotherapy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment72 (estimated)
Ages18 Years and up
SexAll
SponsorAssistance Publique - Hôpitaux de Paris Academic / other
Locations5 sites (Bobigny and 4 other locations)
Trial IDNCT06083090 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of yoga therapy compared to traditional physiotherapy in patients with moderate axial spondyloarthritis (axSPA). It aims to assess improvements in physical symptoms such as pain and stiffness, as well as psychological aspects like anxiety and fatigue. Participants will be randomly assigned to either yoga therapy or physiotherapy, with outcomes measured over a specified period. The study seeks to provide evidence for non-drug therapeutic approaches in managing axSPA.

Who should consider this trial

Good fit: Ideal candidates are French-speaking adults aged 18 and over with a diagnosis of moderately active to active axial spondyloarthritis.

Not a fit: Patients who are pregnant, have recently given birth, or have practiced yoga in the last six months may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could offer a non-drug treatment option that improves the quality of life for patients with axial spondyloarthritis.

How similar studies have performed: Previous studies have shown positive outcomes for yoga therapy in chronic rheumatic conditions, indicating potential success for this approach in axSPA.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* French-speaking patient aged 18 and over
* Patient with axial spondyloarthritis (axSPA) according to Assessment of SpondyloArthritis International Society, diagnosed by a rheumatologist
* "Moderately active" to "active" form of axSPA (basic BASDAI \> 3)
* Stable disease: No recent or foreseeable introduction in the next 6 months of drug treatments for axSPA (excluding analgesics)
* Absence of disabling stress urinary incontinence
* Geographical or organizational possibility of undergoing the study
* Patient informed and having signed the informed consent form for participation in the research

Exclusion Criteria:

* Pregnancy or breastfeeding
* Recent childbirth (within the last six months)
* Patient already practicing yoga or having practiced it in the last six months
* Abdominal or spinal surgery in the last six months
* Motor neurological deficit
* Sphincter deficit
* Any other somatic pathology preventing the practice of physiotherapy or yogatherapy according to the opinion of the evaluating clinician
* Depressive syndrome requiring specific treatment
* Non-affiliation to a social security scheme (beneficiary or beneficiary) or to another social protection scheme
* Patient deprived of liberty by judicial or administrative decision or under legal protection (guardianship, safeguard of justice)
* Currently participating in or in a period of exclusion from: another interventional research involving human participants, a clinical trial on a medical product for human, a clinical investigation on a medical device. Participation in non-interventional research is authorized.

Where this trial is running

Bobigny and 4 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Axial SpondyloarthritisYogatherapyAnkylosing SpondyloarthritisPhysiotherapyYogaRheumatism
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.