Comparing weight gain in children with autism taking two medications

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effects of two FDA-approved medications, aripiprazole and risperidone, on weight gain in children with autism spectrum disorder who exhibit behavioral dysregulation. Conducted in a real-world clinical setting, the trial aims to determine which medication is associated with less weight gain. Participants must be under 18 years old, diagnosed with autism, and naïve to atypical antipsychotic treatment. The study will help inform treatment choices and address the cardiometabolic risks associated with these medications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age 17 years and younger
* diagnosed with autism
* have behavior problems
* seen in Vanderbilt clinic
* naïve to atypical antipsychotics

Exclusion Criteria:

* 18 years or older
* history of atypical antipsychotic use
* not diagnosed with autism

Where it's running

• Division of Developmental Medicine
  Nashville, Tennessee, United States Recruiting

Study contacts

• Principal investigator: Angela Maxwell-Horn, M.D. — Vanderbilt University Medical Center
• Study coordinator: Angela Maxwell-Horn, M.D.
• Email: angela.c.maxwell-horn@vumc.org
• Phone: (615) 936-0249

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.