Comparing waveform capnography and color-change CO2 detectors to confirm tube placement during intubation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational multicenter study will record use of waveform capnography and colorimetric CO2 detectors during tracheal intubation in adult patients cared for in emergency departments and intensive care units. Clinicians will use the exhaled CO2 device they intend to use for confirmation, and researchers will collect device readings and clinical confirmation data. The study will compare sensitivity, specificity, and timing of confirmation for the two device types across procedures at three hospitals. The primary aim is to determine which method more reliably identifies tracheal versus esophageal tube placement in critically ill adults.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patient is located in a participating unit (ED or ICU)
2. Patient is undergoing tracheal intubation.
3. The clinician intends to use an exhaled CO2 detection device to confirm tracheal placement of the tube.

Exclusion Criteria:

1. Patient is known to be a prisoner
2. Patient is known to be \< 18 years old
3. A responsible clinician has determined that sole use of either waveform capnography or colorimetric testing is required for optimal care of the patient.

Where it's running

• Lahey Hospital & Medical Center
  Burlington, Massachusetts, United States Recruiting
• Hennepin Healthcare
  Minneapolis, Minnesota, United States Recruiting
• Regions Hospital
  Saint Paul, Minnesota, United States Recruiting
• Albany Medical Center
  Albany, New York, United States Recruiting
• Wake Forest School of Medicine
  Winston-Salem, North Carolina, United States Recruiting
• The Ohio State University College of Medicine
  Columbus, Ohio, United States Recruiting

Study contacts

• Study coordinator: Brian Driver, MD
• Email: brian.driver@hcmed.org
• Phone: 6128737448

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.