Comparing visual performance of a new intraocular lens for cataract patients

Difference in Visual Performance of a Refractive Extended Depth of Focus Intraocular Lens in an Emmetropic or Monovision Modality

Not applicable Interventional Vienna Institute for Research in Ocular Surgery · NCT06624826

This study is testing a new type of eye lens for cataract patients to see if it can help them see clearly at different distances without needing glasses.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages21 Years to 105 Years
SexAll
SponsorVienna Institute for Research in Ocular Surgery Academic / other
Locations1 site (Vienna, Austria)
Trial IDNCT06624826 on ClinicalTrials.gov

What this trial studies

This study evaluates the visual performance of a new refractive extended depth of focus intraocular lens (IOL) in patients with age-related bilateral cataracts. It compares two modalities: emmetropic and monovision, aiming to achieve spectacle independence for various distances. The study focuses on the lens's ability to provide a continuous range of vision, particularly for intermediate distances, while minimizing issues like dysphotopsia. Participants will undergo surgery and be monitored for visual outcomes post-implantation.

Who should consider this trial

Good fit: Ideal candidates include adults aged 21 and older with age-related bilateral cataracts and specific visual acuity requirements.

Not a fit: Patients with active ocular diseases or significant prior ocular surgeries may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved visual outcomes and reduced reliance on glasses for patients with cataracts.

How similar studies have performed: Previous studies have shown promise with extended depth of focus IOLs, suggesting potential for success with this new approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age-related bilateral cataract
* Age 21 or older
* Visual acuity \> 0.05
* Axial length: 21.00-27.00mm
* Normal findings in the medical history and physical examination unless the investigator considers an abnormality to be clinically relevant
* Written informed consent prior to surgery

Exclusion Criteria:

* Active ocular disease (e.g chronic uveitis, diabetic retinopathy, chronic glaucoma not responsive to medication, corneal dystrophies, etc.) precluding good post-operative visual acuity
* Relevant other ophthalmic diseases such as pseudoexfoliation syndrome (PEX)
* Irregular astigmatism on corneal tomography
* Pronounced dry eye disease
* Previous ocular surgery or trauma
* Persons who are pregnant or nursing (pregnancy test will be taken in women of reproductive age)

Where this trial is running

Vienna, Austria

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cataract
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.