Comparing ventilation methods during abdominal surgery
Power Dissipation in Low Tidal Volume Versus Individualized Flow-controlled Ventilation - a Randomized, Clinical Cross-over Trial
NA · Medical University Innsbruck · NCT06222463
This study is testing if a new way of helping patients breathe during open abdominal surgery is better than the standard method to improve their recovery.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Medical University Innsbruck (other) |
| Locations | 1 site (Innsbruck, Tyrol) |
| Trial ID | NCT06222463 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate power dissipation during flow-controlled ventilation compared to standard low tidal volume ventilation in patients undergoing open abdominal surgery. Participants will be randomly assigned to receive either low tidal volume ventilation or individualized flow-controlled ventilation, with various respiratory parameters measured throughout the procedure. The study focuses on optimizing mechanical ventilation settings to improve patient outcomes during surgery.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older scheduled for elective open abdominal surgery under general anesthesia.
Not a fit: Patients undergoing emergency surgery or classified as American Society of Anesthesiologists Classification IV-V may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance ventilation strategies, leading to better oxygenation and reduced complications during abdominal surgeries.
How similar studies have performed: While the approach of individualized flow-controlled ventilation is being explored, this specific comparison of power dissipation in these settings is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male and female subjects ≥ 18 years * Body weight ≥ 40 kg * Elective open abdominal surgery under general anaesthesia - American Society of Anesthesiologists Classification I-III * Written informed consent Exclusion Criteria: * Emergency surgery * American Society of Anesthesiologists Classification IV-V * Female subjects known to be pregnant * Known participation in another interventional clinical trial
Where this trial is running
Innsbruck, Tyrol
- Medical University of Innsbruck — Innsbruck, Tyrol, Austria (RECRUITING)
Study contacts
- Principal investigator: Patrick Spraider, PhD — Medical University of Innsbruck, Department of Anesthesia and Intensive Care Medicine
- Study coordinator: Patrick Spraider, PhD
- Email: patrick.spraider@i-med.ac.at
- Phone: +43 512 504 80329
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Mechanical Ventilation, Abdominal Surgery, Flow-controlled Ventilation, Power Dissipation, Mechanical Power