Comparing ultrasound imaging techniques for ulcerative colitis

Comparing Three Modalities (Trans Abdominal, Trans-perineal and Endoscopic Ultrasound) of Ultrasonography for Rectal Imaging in Ulcerative Colitis: the TRINITY Study

NA · Asian Institute of Gastroenterology, India · NCT06717906

This study is trying to see if different ultrasound methods can help doctors better understand the condition of the rectal wall in adults with ulcerative colitis.

Quick facts

PhaseNA
Study typeInterventional
Enrollment170 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorAsian Institute of Gastroenterology, India (other)
Locations1 site (Hyderabad)
Trial IDNCT06717906 on ClinicalTrials.gov

What this trial studies

This study evaluates the correlation of rectal wall thickness and vascularity measurements using trans-abdominal ultrasound (TAS), trans-perineal ultrasound (TPUS), and endoscopic ultrasound (EUS) in adults with ulcerative colitis. The primary objective is to correlate rectal wall thickness measured by TPUS with EUS findings, while secondary objectives include assessing the relationship between these measurements and endoscopic and histologic activity. Patients will undergo clinical assessments and various ultrasound techniques, with additional sigmoidoscopy and EUS performed if clinically indicated. The study aims to improve patient management based on these imaging techniques.

Who should consider this trial

Good fit: Ideal candidates are adult patients aged 18-75 with a diagnosis of ulcerative colitis.

Not a fit: Patients who are pregnant, lactating, or do not require endoscopy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the accuracy of diagnosing and managing ulcerative colitis through improved imaging techniques.

How similar studies have performed: Other studies have shown promise in using ultrasound techniques for assessing inflammatory bowel diseases, but this specific approach is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients (18-75 years) with Ulcerative colitis

Exclusion Criteria:

* Pregnant
* Lactating mother
* Endoscopy not required
* No consent

Where this trial is running

Hyderabad

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Ulcerative Colitis

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.