Comparing ultrasound-guided nerve block and medication for chronic migraine prevention
Chronic Migraine Prophylaxis: Comparative Study Between Ultrasound-Guided Greater Occipital Nerve Block and Medical Treatment
This study is testing whether a special nerve block using ultrasound can help adults with chronic migraines feel better compared to regular medication.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta, El-Gharbia) |
| Trial ID | NCT06122545 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of ultrasound-guided greater occipital nerve block using either local anesthetic or botulinum toxin compared to standard medical treatment for preventing chronic migraines. Chronic migraine is characterized by frequent headache days and can significantly impair quality of life. The study will involve adult participants diagnosed with chronic migraine, assessing the outcomes of nerve block techniques against conventional pharmacotherapy. The goal is to determine if these minimally invasive procedures can provide better relief and reduce headache frequency.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who have been diagnosed with chronic migraine.
Not a fit: Patients with medication overuse headaches or those who have recently used acute pain medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could offer a more effective preventive treatment option for patients suffering from chronic migraines.
How similar studies have performed: Previous studies have shown promise in using nerve blocks for migraine treatment, suggesting that this approach may be effective, although this specific comparison is less commonly tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age \> 18 years old. 2. Both sexes. 3. Patients with chronic migraine. Exclusion Criteria: 1. Age less than 18 years. 2. Patients with medication overuse headache. 3. Patients who had used acute pain medications within 24 hours prior to the study visit. 4. History of injury to the area of the GON. 5. Any prior adverse reactions to local anesthetics. 6. Patients with impaired sensation in the occipital area. 7. Any neurological or dermatological disease that may have affected skin sensation, bleeding tendency, any skull defect.
Where this trial is running
Tanta, El-Gharbia
- Tanta University — Tanta, El-Gharbia, Egypt (Recruiting)
Study contacts
- Study coordinator: Sarah Z Elramady, Master
- Email: sara.zakria@med.tanta.edu.eg
- Phone: 00201122848960
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.