Comparing two types of videolaryngoscope blades for intubation in ICU patients

A Randomized Comparison Between the Hyperangulated vs. Macintosh Blades for First-attempt Intubation Success With Videolaryngoscopy in ICU Patients.

Not applicable Interventional Hospital Clinico Universitario de Santiago · NCT06322719

This study is testing whether a new type of videolaryngoscope blade can help doctors more successfully intubate patients in the ICU compared to the standard blade.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1036 (estimated)
Ages18 Years to 90 Years
SexAll
SponsorHospital Clinico Universitario de Santiago Academic / other
Locations29 sites (Santiago de Compostela, A Coruña and 28 other locations)
Trial IDNCT06322719 on ClinicalTrials.gov

What this trial studies

This study aims to compare the effectiveness of hyperangulated and Macintosh videolaryngoscope blades for tracheal intubation in patients admitted to the intensive care unit (ICU). It is a prospective multicenter randomized trial that focuses on the success rate of first-attempt intubation using these two different blade types. The study is based on the hypothesis that hyperangulated blades may lead to higher success rates in intubation compared to the traditional Macintosh blades. The findings could provide valuable insights into optimizing airway management in critically ill patients.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 years or older who are admitted to the ICU and require tracheal intubation using a videolaryngoscope.

Not a fit: Patients who may not benefit from this study include those requiring emergent intubation that does not allow for randomization or those needing intubation with devices other than videolaryngoscopes.

Why it matters

Potential benefit: If successful, this study could enhance the success rate of tracheal intubation in ICU patients, potentially reducing complications and improving patient outcomes.

How similar studies have performed: Previous studies have shown that videolaryngoscopes can improve intubation success rates, making this approach promising but still requiring further investigation into the best blade type.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 years or older.
* Admitted to an Intensive Care Unit.
* Need for tracheal intubation during the stay in the ICU.
* The device to be used for intubation is a videolaryngoscope

Exclusion Criteria:

* Pregnancy or lactation.
* Emergent tracheal intubation that does not allow for the randomization of the procedure.
* Need for tracheal intubation with a device other than the videolaryngoscope (fiberoptic bronchoscope, direct laryngoscopy, tracheostomy, etc.).
* Tracheal intubation performed outside the ICU (Emergency Department, Hospital ward, etc.).

Where this trial is running

Santiago de Compostela, A Coruña and 28 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Acute Respiratory FailureIntubationDifficult or FailedVideolaryngoscopyIntubation Complicationvideolaryngoscopytracheal intubationcomplication
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.