Comparing two types of tendon grafts for ACL reconstruction
The Comparison of Tunnel Morphology and Graft Healing in Anterior Cruciate Ligament Reconstructions Using Peroneus Longus And Hamstring Tendons
This study is testing which of two types of tendon grafts, from the peroneus longus or hamstring, works better for healing after ACL surgery in people aged 18 to 45.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 58 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | Karadeniz Technical University Academic / other |
| Locations | 1 site (Trabzon) |
| Trial ID | NCT06769711 on ClinicalTrials.gov |
What this trial studies
This study compares the healing and integration of two different tendon grafts, the peroneus longus and hamstring tendons, used in anterior cruciate ligament (ACL) reconstruction surgeries. Patients aged 18 to 45 with ACL injuries will be randomly assigned to one of the two graft groups. The study will utilize Magnetic Resonance Imaging (MRI) and Computerized Tomography (CT) to assess graft maturation and tunnel morphology at various intervals post-surgery. Additionally, clinical assessments will be conducted to evaluate knee stability and function in relation to the grafts used.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 18 to 45 with a confirmed ACL injury who are suitable for tendon graft harvesting.
Not a fit: Patients with a history of previous knee or ankle surgery, multiple ligament injuries, or advanced osteoporosis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and rehabilitation strategies for patients undergoing ACL reconstruction.
How similar studies have performed: While similar studies have explored tendon grafts in ACL reconstruction, this specific comparison of peroneus longus and hamstring tendons is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged between 18 and 45 years. * BMI in the range of 18 to 28. * Diagnosed with an anterior cruciate ligament (ACL) injury preoperatively confirmed by MRI. * Patients for whom it is deemed appropriate to harvest ipsilateral hamstring tendons or Peroneus Longus tendon for use as a graft. Exclusion Criteria: * History of previous surgery on the affected knee or ankle. * Presence of multiple ligament injuries in the affected knee. * Diagnosis of advanced osteoporosis. * ACL injuries that occurred more than 12 months prior to surgery. * Evidence of unstable meniscal injury on preoperative MRI, which may alter the postoperative rehabilitation process. * Evidence of unstable meniscal injury on preoperative MRI, which may alter the postoperative rehabilitation process.
Where this trial is running
Trabzon
- Karadeniz Technical University, Orthopedic and Traumatology Department — Trabzon, Turkey (Recruiting)
Study contacts
- Study coordinator: Fevzi Gurkan Aslan, Medical Doctor
- Email: fevzigurkanaslan@yahoo.com
- Phone: +905377085171
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.